Novel opportunities for CFTR-targeting drug development using organoids

Por Dekkers, Johanna F, van der Ent, Cornelis K, Beekman, Jeffrey M
Publicado em 2013

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients

Por Boj, Sylvia F., Vonk, Annelotte M., Statia, Marvin, Su, Jinyi, Dekkers, Johanna F., Vries, Robert R. G., Beekman, Jeffrey M., Clevers, Hans
Publicado no J Vis Exp (2017)

Mechanism-based corrector combination restores ΔF508-CFTR folding and function

Por Okiyoneda, Tsukasa, Veit, Guido, Dekkers, Johanna F., Bagdany, Miklos, Soya, Naoto, Xu, Haijin, Roldan, Ariel, Verkman, Alan S., Kurth, Mark, Simon, Agnes, Hegedus, Tamas, Beekman, Jeffrey M., Lukacs, Gergely L.
Publicado em 2013

Modulation of the Maladaptive Stress Response to Manage Diseases of Protein Folding

Por Roth, Daniela Martino, Hutt, Darren M., Tong, Jiansong, Bouchecareilh, Marion, Wang, Ning, Seeley, Theo, Dekkers, Johanna F., Beekman, Jeffrey M., Garza, Dan, Drew, Lawrence, Masliah, Eliezer, Morimoto, Richard I., Balch, William E.
Publicado no PLoS Biol (2014)

Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis

Por Alton, Eric W F W, Beekman, Jeffery M, Boyd, A Christopher, Brand, June, Carlon, Marianne S, Connolly, Mary M, Chan, Mario, Conlon, Sinead, Davidson, Heather E, Davies, Jane C, Davies, Lee A, Dekkers, Johanna F, Doherty, Ann, Gea-Sorli, Sabrina, Gill, Deborah R, Griesenbach, Uta, Hasegawa, Mamoru, Higgins, Tracy E, Hironaka, Takashi, Hyndman, Laura, McLachlan, Gerry, Inoue, Makoto, Hyde, Stephen C, Innes, J Alastair, Maher, Toby M, Moran, Caroline, Meng, Cuixiang, Paul-Smith, Michael C, Pringle, Ian A, Pytel, Kamila M, Rodriguez-Martinez, Andrea, Schmidt, Alexander C, Stevenson, Barbara J, Sumner-Jones, Stephanie G, Toshner, Richard, Tsugumine, Shu, Wasowicz, Marguerite W, Zhu, Jie
Publicado no Thorax (2017)