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Modulation of the Maladaptive Stress Response to Manage Diseases of Protein Folding

Diseases of protein folding arise because of the inability of an altered peptide sequence to properly engage protein homeostasis components that direct protein folding and function. To identify global principles of misfolding disease pathology we examined the impact of the local folding environment...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Roth, Daniela Martino, Hutt, Darren M., Tong, Jiansong, Bouchecareilh, Marion, Wang, Ning, Seeley, Theo, Dekkers, Johanna F., Beekman, Jeffrey M., Garza, Dan, Drew, Lawrence, Masliah, Eliezer, Morimoto, Richard I., Balch, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236052/
https://ncbi.nlm.nih.gov/pubmed/25406061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001998
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