Modulation of the Maladaptive Stress Response to Manage Diseases of Protein Folding

Diseases of protein folding arise because of the inability of an altered peptide sequence to properly engage protein homeostasis components that direct protein folding and function. To identify global principles of misfolding disease pathology we examined the impact of the local folding environment...

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Bibliographic Details
Published in:PLoS Biol
Main Authors: Roth, Daniela Martino, Hutt, Darren M., Tong, Jiansong, Bouchecareilh, Marion, Wang, Ning, Seeley, Theo, Dekkers, Johanna F., Beekman, Jeffrey M., Garza, Dan, Drew, Lawrence, Masliah, Eliezer, Morimoto, Richard I., Balch, William E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236052/
https://ncbi.nlm.nih.gov/pubmed/25406061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001998
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