Epistasis of Transcriptomes Reveals Synergism between Transcriptional Activators Hnf1α and Hnf4α

по Boj, Sylvia F., Petrov, Dimitri, Ferrer, Jorge
Опубликовано 2010

A transcription factor regulatory circuit in differentiated pancreatic cells

по Boj, Sylvia F., Párrizas, Marcelina, Maestro, Miguel A., Ferrer, Jorge
Опубликовано 2001

Pre-clinical Models of Pancreatic Ductal Adenocarcinoma

по Hwang, Chang-II, Boj, Sylvia F., Clevers, Hans, Tuveson, David A.
Опубликовано в: J Pathol (2015)

Functional Targets of the Monogenic Diabetes Transcription Factors HNF-1α and HNF-4α Are Highly Conserved Between Mice and Humans

по Boj, Sylvia F., Servitja, Joan Marc, Martin, David, Rios, Martin, Talianidis, Iannis, Guigo, Roderic, Ferrer, Jorge
Опубликовано 2009

Model organoids provide new research opportunities for ductal pancreatic cancer

по Boj, Sylvia F, Hwang, Chang-Il, Baker, Lindsey A, Engle, Dannielle D, Tuveson, David A, Clevers, Hans
Опубликовано в: Mol Cell Oncol (2015)

Hepatic Nuclear Factor 1-α Directs Nucleosomal Hyperacetylation to Its Tissue-Specific Transcriptional Targets

по Párrizas, Marcelina, Maestro, Miguel A., Boj, Sylvia F., Paniagua, Amaya, Casamitjana, Roser, Gomis, Ramon, Rivera, Francisca, Ferrer, Jorge
Опубликовано 2001

Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

по Wensink, G. Emerens, Elias, Sjoerd G., Mullenders, Jasper, Koopman, Miriam, Boj, Sylvia F., Kranenburg, Onno W., Roodhart, Jeanine M. L.
Опубликовано в: NPJ Precis Oncol (2021)

Macrosomia and Hyperinsulinaemic Hypoglycaemia in Patients with Heterozygous Mutations in the HNF4A Gene

по Pearson, Ewan R, Boj, Sylvia F, Steele, Anna M, Barrett, Timothy, Stals, Karen, Shield, Julian P, Ellard, Sian, Ferrer, Jorge, Hattersley, Andrew T
Опубликовано 2007

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients

по Boj, Sylvia F., Vonk, Annelotte M., Statia, Marvin, Su, Jinyi, Dekkers, Johanna F., Vries, Robert R. G., Beekman, Jeffrey M., Clevers, Hans
Опубликовано в: J Vis Exp (2017)

Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses

по Raimondi, Giulia, Mato-Berciano, Ana, Pascual-Sabater, Silvia, Rovira-Rigau, Maria, Cuatrecasas, Miriam, Fondevila, Constantino, Sánchez-Cabús, Santiago, Begthel, Harry, Boj, Sylvia F., Clevers, Hans, Fillat, Cristina
Опубликовано в: EBioMedicine (2020)

Hnf1α (MODY3) Controls Tissue-Specific Transcriptional Programs and Exerts Opposed Effects on Cell Growth in Pancreatic Islets and Liver

по Servitja, Joan-Marc, Pignatelli, Miguel, Maestro, Miguel Ángel, Cardalda, Carina, Boj, Sylvia F., Lozano, Juanjo, Blanco, Enrique, Lafuente, Amàlia, McCarthy, Mark I., Sumoy, Lauro, Guigó, Roderic, Ferrer, Jorge
Опубликовано 2009

A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal

по van Es, Johan H., Haegebarth, Andrea, Kujala, Pekka, Itzkovitz, Shalev, Koo, Bon-Kyoung, Boj, Sylvia F., Korving, Jeroen, van den Born, Maaike, van Oudenaarden, Alexander, Robine, Sylvie, Clevers, Hans
Опубликовано 2012

The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis

по Mahmoudi, Tokameh, Boj, Sylvia F., Hatzis, Pantelis, Li, Vivian S. W., Taouatas, Nadia, Vries, Robert G. J., Teunissen, Hans, Begthel, Harry, Korving, Jeroen, Mohammed, Shabaz, Heck, Albert J. R., Clevers, Hans
Опубликовано 2010

Correction: The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis

по Mahmoudi, Tokameh, Boj, Sylvia F., Hatzis, Pantelis, Li, Vivian S. W., Taouatas, Nadia, Vries, Robert G. J., Teunissen, Hans, Begthel, Harry, Korving, Jeroen, Mohammed, Shabaz, Heck, Albert J. R., Clevers, Hans
Опубликовано в: PLoS Biol (2017)

Generation and initial characterization of novel tumour organoid models to study human pancreatic cancer‐induced cachexia

по Vaes, Rianne D.W., van Dijk, David P.J., Welbers, Tessa T.J., Blok, Marinus J., Aberle, Merel R., Heij, Lara, Boj, Sylvia F., Olde Damink, Steven W.M., Rensen, Sander S.
Опубликовано в: J Cachexia Sarcopenia Muscle (2020)

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

по Huch, Meritxell, Dorrell, Craig, Boj, Sylvia F., van Es, Johan H., van de Wetering, Marc, Li, Vivian S.W., Hamer, Karien, Sasaki, Nobuo, Finegold, Milton J., Haft, Annelise, Grompe, Markus, Clevers, Hans
Опубликовано 2013

G970R‐CFTR Mutation (c.2908G>C) Results Predominantly in a Splicing Defect

по Fidler, Meredith C., Buckley, Alexandra, Sullivan, James C., Statia, Marvin, Boj, Sylvia F., Vries, Robert G. J., Munck, Anne, Higgins, Mark, Moretto Zita, Matteo, Negulescu, Paul, van Goor, Fredrick, De Boeck, Kris
Опубликовано в: Clin Transl Sci (2020)

Genetic evidence that HNF-1α–dependent transcriptional control of HNF-4α is essential for human pancreatic β cell function

по Hansen, Sara K., Párrizas, Marcelina, Jensen, Maria L., Pruhova, Stepanka, Ek, Jakob, Boj, Sylvia F., Johansen, Anders, Maestro, Miguel A., Rivera, Francisca, Eiberg, Hans, Andel, Michal, Lebl, Jan, Pedersen, Oluf, Ferrer, Jorge, Hansen, Torben
Опубликовано 2002

Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids

по Dekkers, Johanna F., van Vliet, Esmée J., Sachs, Norman, Rosenbluth, Jennifer M., Kopper, Oded, Rebel, Heggert G., Wehrens, Ellen J., Piani, Carol, Visvader, Jane E., Verissimo, Carla S., Boj, Sylvia F., Brugge, Joan S., Clevers, Hans, Rios, Anne C.
Опубликовано в: Nat Protoc (2021)

EuroDia: a beta-cell gene expression resource

по Liechti, Robin, Csárdi, Gábor, Bergmann, Sven, Schütz, Frédéric, Sengstag, Thierry, Boj, Sylvia F., Servitja, Joan-Marc, Ferrer, Jorge, Van Lommel, Leentje, Schuit, Frans, Klinger, Sonia, Thorens, Bernard, Naamane, Najib, Eizirik, Decio L., Marselli, Lorella, Bugliani, Marco, Marchetti, Piero, Lucas, Stephanie, Holm, Cecilia, Jongeneel, C. Victor, Xenarios, Ioannis
Опубликовано 2010