Epistasis of Transcriptomes Reveals Synergism between Transcriptional Activators Hnf1α and Hnf4α

The transcription of individual genes is determined by combinatorial interactions between DNA–binding transcription factors. The current challenge is to understand how such combinatorial interactions regulate broad genetic programs that underlie cellular functions and disease. The transcription fact...

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Bibliographic Details
Main Authors: Boj, Sylvia F., Petrov, Dimitri, Ferrer, Jorge
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877749/
https://ncbi.nlm.nih.gov/pubmed/20523905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000970
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