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Negative autoregulation of HNF-4α gene expression by HNF-4α1

HNF-4α (hepatocyte nuclear factor-4α) is required for tissue-specific expression of many of the hepatic, pancreatic, enteric and renal traits. Heterozygous HNF-4α mutants are inflicted by MODY-1 (maturity onset diabetes of the young type-1). HNF-4α expression is reported here to be negatively autore...

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Detalhes bibliográficos
Main Authors: Magenheim, Judith, Hertz, Rachel, Berman, Ina, Nousbeck, Janna, Bar-Tana, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186722/
https://ncbi.nlm.nih.gov/pubmed/15651981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041802
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