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Crystallization of hepatocyte nuclear factor 4α (HNF4α) in complex with the HNF1α promoter element
Hepatocyte nuclear factor 4α (HNF4α) is a member of the nuclear receptor superfamily that plays a central role in organ development and metabolic functions. Mutations on HNF4α cause maturity-onset diabetes of the young (MODY), a dominant monogenic cause of diabetes. In order to understand the molecu...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
International Union of Crystallography
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374247/ https://ncbi.nlm.nih.gov/pubmed/18391435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108007136 |
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