Structural Basis of Natural Promoter Recognition by a Unique Nuclear Receptor, HNF4α: DIABETES GENE PRODUCT

HNF4α (hepatocyte nuclear factor 4α) plays an essential role in the development and function of vertebrate organs, including hepatocytes and pancreatic β-cells by regulating expression of multiple genes involved in organ development, nutrient transport, and diverse metabolic pathways. As such, HNF4α...

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Bibliographic Details
Main Authors: Lu, Peng, Rha, Geun Bae, Melikishvili, Manana, Wu, Guangteng, Adkins, Brandon C., Fried, Michael G., Chi, Young-In
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Transcription, Chromatin, and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586258/
https://ncbi.nlm.nih.gov/pubmed/18829458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806213200
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