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Pattern of genes influenced by conditional expression of the transcription factors HNF6, HNF4α and HNF1β in a pancreatic β-cell line

Using the rat insulinoma cell line INS-1 we generated β-cell clones that are most efficient for gene transfer, as they contain an FRT site for Flp recombinase-mediated, site-directed integration of a single copy transgene. Therefore, the gene-of-interest can be introduced by DNA transfection without...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Thomas, Heike, Senkel, Sabine, Erdmann, Silke, Arndt, Tanja, Turan, Gülüzar, Klein-Hitpass, Ludger, Ryffel, Gerhart U.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC528820/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15520459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh144
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