Pattern of genes influenced by conditional expression of the transcription factors HNF6, HNF4α and HNF1β in a pancreatic β-cell line

Using the rat insulinoma cell line INS-1 we generated β-cell clones that are most efficient for gene transfer, as they contain an FRT site for Flp recombinase-mediated, site-directed integration of a single copy transgene. Therefore, the gene-of-interest can be introduced by DNA transfection without...

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Bibliographic Details
Main Authors: Thomas, Heike, Senkel, Sabine, Erdmann, Silke, Arndt, Tanja, Turan, Gülüzar, Klein-Hitpass, Ludger, Ryffel, Gerhart U.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2004
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NAR Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC528820/
https://ncbi.nlm.nih.gov/pubmed/15520459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh144
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