Lack of Repeat Transduction by Recombinant Adeno-Associated Virus Type 5/5 Vectors in the Mouse Airway

Por Sumner-Jones, Stephanie G., Gill, Deborah R., Hyde, Stephen C.
Publicado em 2007

A Phase I/IIa Safety and Efficacy Study of Nebulized Liposome-mediated Gene Therapy for Cystic Fibrosis Supports a Multidose Trial

Por Alton, Eric W. F. W., Boyd, A. Christopher, Porteous, David J., Davies, Gwyneth, Davies, Jane C., Griesenbach, Uta, Higgins, Tracy E., Gill, Deborah R., Hyde, Stephen C., Innes, J. Alastair
Publicado no Am J Respir Crit Care Med (2015)

Human-Mouse Chimeras With Normal Expression and Function Reveal That Major Domain Swapping is Tolerated by P-glycoprotein (ABCB1)

Por Pluchino, Kristen M., Hall, Matthew D., Moen, Janna K., Chufan, Eduardo E., Fetsch, Patricia A., Shukla, Suneet, Gill, Deborah R., Hyde, Stephen C., Xia, Di, Ambudkar, Suresh V., Gottesman, Michael M.
Publicado no Biochemistry (2016)

Self-Reactive CFTR T Cells in Humans: Implications for Gene Therapy

Por Calcedo, Roberto, Griesenbach, Uta, Dorgan, Daniel J., Soussi, Samia, Boyd, A. Christopher, Davies, Jane C., Higgins, Tracy E., Hyde, Stephen C., Gill, Deborah R., Innes, J. Alastair, Porteous, David J., Alton, Eric W., Wilson, James M., Limberis, Maria P.
Publicado em 2013

Identification of a Cryptic Bacterial Promoter in Mouse (mdr1a) P-Glycoprotein cDNA

Por Pluchino, Kristen M., Esposito, Dominic, Moen, Janna K., Hall, Matthew D., Madigan, James P., Shukla, Suneet, Procter, Lauren V., Wall, Vanessa E., Schneider, Thomas D., Pringle, Ian, Ambudkar, Suresh V., Gill, Deborah R., Hyde, Steven C., Gottesman, Michael M.
Publicado no PLoS One (2015)

Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo

Por Hu Jim, Chow Yu-Hua, Hyde Stephen C, Gill Deborah R, Smith Rbecca L, Painter Hazel, Somerton Luci, Singh Charanjit, Farley Raymond, Garcia Sara, Kitson Chris, Griesenbach Uta, Gray Mike, Edbrooke Mark, Ogilvie Varrie, MacGregor Gordon, Scheule Ronald K, Cheng Seng H, Caplen Natasha J, Alton Eric WFW
Publicado em 2006-02-01

Assessment of F/HN-Pseudotyped Lentivirus as a Clinically Relevant Vector for Lung Gene Therapy

Por Griesenbach, Uta, Inoue, Makoto, Meng, Cuixiang, Farley, Raymond, Chan, Mario, Newman, Nikki K., Brum, Andrea, You, Jun, Kerton, Angela, Shoemark, Amelia, Boyd, A. Christopher, Davies, Jane C., Higgins, Tracy E., Gill, Deborah R., Hyde, Stephen C., Innes, J. Alastair, Porteous, David J., Hasegawa, Mamoru, Alton, Eric W. F. W.
Publicado em 2012

Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo

Por Griesenbach, Uta, Kitson, Chris, Garcia, Sara Escudero, Farley, Raymond, Singh, Charanjit, Somerton, Luci, Painter, Hazel, Smith, Rbecca L, Gill, Deborah R, Hyde, Stephen C, Chow, Yu-Hua, Hu, Jim, Gray, Mike, Edbrooke, Mark, Ogilvie, Varrie, MacGregor, Gordon, Scheule, Ronald K, Cheng, Seng H, Caplen, Natasha J, Alton, Eric WFW
Publicado em 2006

The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways

Por Griesenbach, Uta, Meng, Cuixiang, Farley, Raymond, Wasowicz, Marguerite, Munkonge, Felix M, Chan, Mario, Stoneham, Charlotte, Sumner-Jones, Stephanie, Pringle, Ian A., Gill, Deborah R., Hyde, Stephen C., Stevenson, Barbara, Holder, Emma, Ban, Hiroshi, Hasegawa, Mamoru, Cheng, Seng H, Scheule, Ronald K, Sinn, Patrick L, McCray, Paul B, Alton, Eric WFW
Publicado em 2009

Identification and Functional Characterization of Cytoplasmic Determinants of Plasmid DNA Nuclear Import

Por Munkonge, Felix M., Amin, Vaksha, Hyde, Stephen C., Green, Anne-Marie, Pringle, Ian A., Gill, Deborah R., Smith, Joel W. S., Hooley, Robert P., Xenariou, Stefania, Ward, Malcolm A., Leeds, Nicola, Leung, Kit-Yi, Chan, Mario, Hillery, Elizabeth, Geddes, Duncan M., Griesenbach, Uta, Postel, Edith H., Dean, David A., Dunn, Michael J., Alton, Eric W. F. W.
Publicado em 2009

Pharmacological Characterization of a Novel ENaCα siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis

Por Clark, Kenneth L, Hughes, Stephen A, Bulsara, Pallav, Coates, Jill, Moores, Kitty, Parry, Joel, Carr, Michael, Mayer, Ruth J, Wilson, Paul, Gruenloh, Chris, Levin, Daren, Darton, Jill, Weber, Wolf-Michael, Sobczak, Katja, Gill, Deborah R, Hyde, Stephen C, Davies, Lee A, Pringle, Ian A, Sumner-Jones, Stephanie G, Jadhav, Vasant, Jamison, Sharon, Strapps, Walter R, Pickering, Victoria, Edbrooke, Mark R
Publicado em 2013

Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis

Por Alton, Eric W F W, Beekman, Jeffery M, Boyd, A Christopher, Brand, June, Carlon, Marianne S, Connolly, Mary M, Chan, Mario, Conlon, Sinead, Davidson, Heather E, Davies, Jane C, Davies, Lee A, Dekkers, Johanna F, Doherty, Ann, Gea-Sorli, Sabrina, Gill, Deborah R, Griesenbach, Uta, Hasegawa, Mamoru, Higgins, Tracy E, Hironaka, Takashi, Hyndman, Laura, McLachlan, Gerry, Inoue, Makoto, Hyde, Stephen C, Innes, J Alastair, Maher, Toby M, Moran, Caroline, Meng, Cuixiang, Paul-Smith, Michael C, Pringle, Ian A, Pytel, Kamila M, Rodriguez-Martinez, Andrea, Schmidt, Alexander C, Stevenson, Barbara J, Sumner-Jones, Stephanie G, Toshner, Richard, Tsugumine, Shu, Wasowicz, Marguerite W, Zhu, Jie
Publicado no Thorax (2017)

Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

Por Alton, Eric W F W, Armstrong, David K, Ashby, Deborah, Bayfield, Katie J, Bilton, Diana, Bloomfield, Emily V, Boyd, A Christopher, Brand, June, Buchan, Ruaridh, Calcedo, Roberto, Carvelli, Paula, Chan, Mario, Cheng, Seng H, Collie, D David S, Cunningham, Steve, Davidson, Heather E, Davies, Gwyneth, Davies, Jane C, Davies, Lee A, Dewar, Maria H, Doherty, Ann, Donovan, Jackie, Dwyer, Natalie S, Elgmati, Hala I, Featherstone, Rosanna F, Gavino, Jemyr, Gea-Sorli, Sabrina, Geddes, Duncan M, Gibson, James S R, Gill, Deborah R, Greening, Andrew P, Griesenbach, Uta, Hansell, David M, Harman, Katharine, Higgins, Tracy E, Hodges, Samantha L, Hyde, Stephen C, Hyndman, Laura, Innes, J Alastair, Jacob, Joseph, Jones, Nancy, Keogh, Brian F, Limberis, Maria P, Lloyd-Evans, Paul, Maclean, Alan W, Manvell, Michelle C, McCormick, Dominique, McGovern, Michael, McLachlan, Gerry, Meng, Cuixiang, Montero, M Angeles, Milligan, Hazel, Moyce, Laura J, Murray, Gordon D, Nicholson, Andrew G, Osadolor, Tina, Parra-Leiton, Javier, Porteous, David J, Pringle, Ian A, Punch, Emma K, Pytel, Kamila M, Quittner, Alexandra L, Rivellini, Gina, Saunders, Clare J, Scheule, Ronald K, Sheard, Sarah, Simmonds, Nicholas J, Smith, Keith, Smith, Stephen N, Soussi, Najwa, Soussi, Samia, Spearing, Emma J, Stevenson, Barbara J, Sumner-Jones, Stephanie G, Turkkila, Minna, Ureta, Rosa P, Waller, Michael D, Wasowicz, Marguerite Y, Wilson, James M, Wolstenholme-Hogg, Paul
Publicado no Lancet Respir Med (2015)