The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters

af Golin, John, Ambudkar, Suresh V.
Udgivet i Biochem J (2015)

ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators

af Lusvarghi, Sabrina, Ambudkar, Suresh V.
Udgivet i Biochem J (2019)

Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein

af Sauna, Zuben E., Ambudkar, Suresh V.
Udgivet 2000

Analysis of Expression of Drug Resistance-Linked ABC Transporters in Cancer Cells by Quantitative RT-PCR

af Calcagno, Anna Maria, Ambudkar, Suresh V.
Udgivet 2010

The molecular mechanisms of drug resistance in single-step and multi-step drug-selected cancer cells

af Calcagno, Anna Maria, Ambudkar, Suresh V.
Udgivet 2010

Discovering Natural Product Modulators to Overcome Multidrug Resistance in Cancer Chemotherapy

af Wu, Chung-Pu, Ohnuma, Shinobu, Ambudkar, Suresh V.
Udgivet 2011

Tyrosine kinase inhibitors as modulators of ABC transporter-mediated drug resistance

af Shukla, Suneet, Chen, Zhe-Sheng, Ambudkar, Suresh V.
Udgivet 2012

Structure of a multidrug transporter: Crystal structures of a mammalian multidrug efflux pump bound to peptide inhibitors may reveal drug binding sites

af Gottesman, Michael M., Ambudkar, Suresh V., Xia, Di
Udgivet 2009

Drug-Protein Hydrogen Bonds Govern the Inhibition of the ATP Hydrolysis of the Multidrug Transporter P-glycoprotein

af Chufan, Eduardo E., Kapoor, Khyati, Ambudkar, Suresh V.
Udgivet i Biochem Pharmacol (2015)

Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and...

af Vahedi, Shahrooz, Chufan, Eduardo E., Ambudkar, Suresh V.
Udgivet i Biochem Pharmacol (2017)

Does the ATP-bound EQ mutant reflect the pre- or post-ATP hydrolysis state in the catalytic cycle of human P-glycoprotein (ABCB1)?

af Lusvarghi, Sabrina, Durell, Stewart R., Ambudkar, Suresh V.
Udgivet i FEBS Lett (2021)

Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: Evaluation of current strategies

af Wu, Chung-Pu, Calcagno, Anna Maria, Ambudkar, Suresh V.
Udgivet 2008

Biochemical Mechanism of Modulation of Human P-glycoprotein by Stemofoline

af Chanmahasathien, Wisinee, Ohnuma, Shinobu, Ambudkar, Suresh V., Limtrakul, Pornngarm
Udgivet 2011

Large-scale purification of functional human P-glycoprotein (ABCB1)

af Nandigama, Krishnamachary, Lusvarghi, Sabrina, Shukla, Suneet, Ambudkar, Suresh V.
Udgivet i Protein Expr Purif (2019)

Molecular Basis of the Polyspecificity of P-Glycoprotein (ABCB1): Recent Biochemical and Structural Studies

af Chufan, Eduardo E., Sim, Hong-May, Ambudkar, Suresh V.
Udgivet i Adv Cancer Res (2015)

The naphthoquinones, vitamin K3 and its structural analog plumbagin, are substrates of the multidrug resistance-linked ABC drug transporter ABCG2

af Shukla, Suneet, Wu, Chung-Pu, Nandigama, Krishnamachary, Ambudkar, Suresh V.
Udgivet 2007

Mutations in Intracellular Loops 1 and 3 Lead to Misfolding of Human P-glycoprotein (ABCB1) That Can Be Rescued by Cyclosporine A, Which Reduces Its Association with Chaperone Hsp7...

af Kapoor, Khyati, Bhatnagar, Jaya, Chufan, Eduardo E., Ambudkar, Suresh V.
Udgivet 2013

A Combination of Curcumin with Either Gramicidin or Ouabain Selectively Kills Cells That Express the Multidrug Resistance-linked ABCG2 Transporter

af Rao, Divya K., Liu, Haiyan, Ambudkar, Suresh V., Mayer, Michael
Udgivet i J Biol Chem (2014)

South Asian Medicinal Compounds as Modulators of Resistance to Chemotherapy and Radiotherapy

af Prasad, N. Rajendra, Muthusamy, Ganesan, Shanmugam, Mohana, Ambudkar, Suresh V.
Udgivet i Cancers (Basel) (2016)

Effects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions

af Shukla, Suneet, Abel, Biebele, Chufan, Eduardo E., Ambudkar, Suresh V.
Udgivet i J Biol Chem (2017)