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A Combination of Curcumin with Either Gramicidin or Ouabain Selectively Kills Cells That Express the Multidrug Resistance-linked ABCG2 Transporter

This paper introduces a strategy to kill selectively multidrug-resistant cells that express the ABCG2 transporter (also called breast cancer resistance protein, or BCRP). The approach is based on specific stimulation of ATP hydrolysis by ABCG2 transporters with subtoxic doses of curcumin combined wi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Rao, Divya K., Liu, Haiyan, Ambudkar, Suresh V., Mayer, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223339/
https://ncbi.nlm.nih.gov/pubmed/25253691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576819
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