Curcumin inhibits the activity of ABCG2/BCRP1, a multidrug resistance-linked ABC drug transporter in mice

PURPOSE: To evaluate the in vivo efficacy of curcumin as an inhibitor of the multidrug-resistance-linked ATP Binding Cassette (ABC) drug transporter, ABCG2. METHODS: Photoaffinity labeling with [(125)I]-iodoarylazidoprazosin was used to characterize the interaction of sulfasalazine, a substrate of t...

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Hlavní autoři: Shukla, Suneet, Zaher, Hani, Hartz, Anika, Bauer, Björn, Ware, Joseph A., Ambudkar, Suresh V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662629/
https://ncbi.nlm.nih.gov/pubmed/18841445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-008-9735-8
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