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Curcumin inhibits the activity of ABCG2/BCRP1, a multidrug resistance-linked ABC drug transporter in mice
PURPOSE: To evaluate the in vivo efficacy of curcumin as an inhibitor of the multidrug-resistance-linked ATP Binding Cassette (ABC) drug transporter, ABCG2. METHODS: Photoaffinity labeling with [(125)I]-iodoarylazidoprazosin was used to characterize the interaction of sulfasalazine, a substrate of t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662629/ https://ncbi.nlm.nih.gov/pubmed/18841445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-008-9735-8 |
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