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Curcumin Modulates Efflux Mediated by Yeast ABC Multidrug Transporters and Is Synergistic with Antifungals

Curcumin (CUR), a natural product of turmeric, from rhizomes of Curcuma longa, is a known agent of reversal of drug resistance phenotypes in cancer cells overexpressing ATP-binding cassette (ABC) transporters, viz., ABCB1, ABCG2, and ABCC1. In the present study, we evaluated whether CUR could also m...

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Autors principals: Sharma, Monika, Manoharlal, Raman, Shukla, Suneet, Puri, Nidhi, Prasad, Tulika, Ambudkar, Suresh V., Prasad, Rajendra
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715616/
https://ncbi.nlm.nih.gov/pubmed/19470507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01497-08
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