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Discovering Natural Product Modulators to Overcome Multidrug Resistance in Cancer Chemotherapy

Multidrug resistance caused by the overexpression of ABC drug transporters is a major obstacle in clinical cancer chemotherapy. For several years, it appeared that direct inhibition of ABC transporters would be the cheapest and most efficient way to combat this problem. Unfortunately, progress in fi...

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Detalhes bibliográficos
Main Authors: Wu, Chung-Pu, Ohnuma, Shinobu, Ambudkar, Suresh V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337630/
https://ncbi.nlm.nih.gov/pubmed/21118092
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