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Discovering Natural Product Modulators to Overcome Multidrug Resistance in Cancer Chemotherapy

Multidrug resistance caused by the overexpression of ABC drug transporters is a major obstacle in clinical cancer chemotherapy. For several years, it appeared that direct inhibition of ABC transporters would be the cheapest and most efficient way to combat this problem. Unfortunately, progress in fi...

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Autors principals: Wu, Chung-Pu, Ohnuma, Shinobu, Ambudkar, Suresh V.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337630/
https://ncbi.nlm.nih.gov/pubmed/21118092
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