Kuguacin J isolated from Momordica charantia leaves inhibits P-glycoprotein (ABCB1)-mediated multidrug resistance

Multidrug-resistance (MDR), a phenomenon in which cancer cells exhibit simultaneous resistance to chemically unrelated drugs, is a major factor in the failure of chemotherapy in cancer patients. Resistance to chemotherapy has been correlated to the overexpression of ABC drug transporters including P...

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Main Authors: Pitchakarn, Pornsiri, Ohnuma, Shinobu, Pintha, Komsak, Pompimon, Wilart, Ambudkar, Suresh V., Limtrakul, Pornngarm
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394403/
https://ncbi.nlm.nih.gov/pubmed/21414769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2010.11.005
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