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Kuguacin J isolated from Momordica charantia leaves inhibits P-glycoprotein (ABCB1)-mediated multidrug resistance
Multidrug-resistance (MDR), a phenomenon in which cancer cells exhibit simultaneous resistance to chemically unrelated drugs, is a major factor in the failure of chemotherapy in cancer patients. Resistance to chemotherapy has been correlated to the overexpression of ABC drug transporters including P...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3394403/ https://ncbi.nlm.nih.gov/pubmed/21414769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2010.11.005 |
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