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Revealing the fate of cell surface human P-glycoprotein (ABCB1): The Lysosomal Degradation Pathway
P-glycoprotein (P-gp) transports a variety of chemically dissimilar amphipathic compounds including anticancer drugs. Although mechanisms of P-gp drug transport are widely studied, the pathways involving its internalization are poorly understood. The present study is aimed at elucidating the pathway...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4558211/ https://ncbi.nlm.nih.gov/pubmed/26057472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.06.001 |
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