Design, synthesis and biological evaluation of (S)-valine thiazole-derived cyclic and non-cyclic peptidomimetic oligomers as modulators of human P-glycoprotein (ABCB1)

Multidrug resistance (MDR) caused by ATP-binding cassette (ABC) transporter P-glycoprotein (P-gp) through extrusion of anticancer drugs from the cells is a major cause of failure to cancer chemotherapy. Previously, selenazole containing cyclic peptides were reported as P-gp inhibitors and these were...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Singh, Satyakam, Prasad, Nagarajan Rajendra, Kapoor, Khyati, Chufan, Eduardo E., Patel, Bhargav A., Ambudkar, Suresh V., Talele, Tanaji T.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905599/
https://ncbi.nlm.nih.gov/pubmed/24288265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300565
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares