Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1

Multidrug resistance (MDR) attenuates the chemotherapy efficacy and increases the probability of cancer recurrence. The accelerated drug efflux mediated by ATP-binding cassette (ABC) transporters is one of the major MDR mechanisms. This study investigated if TTT-28, a newly synthesized thiazole-vali...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Wang, Yi-Jun, Patel, Bhargav A., Anreddy, Nagaraju, Zhang, Yun-Kai, Zhang, Guan-Nan, Alqahtani, Saeed, Singh, Satyakam, Shukla, Suneet, Kaddoumi, Amal, Ambudkar, Suresh V., Talele, Tanaji T., Chen, Zhe-Sheng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299601/
https://ncbi.nlm.nih.gov/pubmed/28181548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42106
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars