Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivo

Multidrug resistance (MDR) is a phenomenon where cancer cells become simultaneously resistant to anticancer drugs with different structures and mechanisms of action. MDR has been shown to be associated with overexpression of ATP-binding cassette (ABC) transporters. Here, we report that telatinib, a...

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Detalhes bibliográficos
Main Authors: Sodani, Kamlesh, Patel, Atish, Anreddy, Nagaraju, Singh, Satyakam, Yang, Dong-Hua, Kathawala, Rishil J, Kumar, Priyank, Talele, Tanaji T, Chen, Zhe-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983711/
https://ncbi.nlm.nih.gov/pubmed/24565910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.02.012
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