Quizartinib (AC220) reverses ABCG2-mediated multidrug resistance: In vitro and in vivo studies

Previous reports have shown that some tyrosine kinase inhibitors (TKIs) could inhibit the ATP-binding cassette (ABC) transporters involved in multidrug resistance (MDR). Quizartinib (AC220), a potent class III receptor tyrosine kinase inhibitor (TKI), was synthesized to selectively inhibit FMS-like...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Jun, Kumar, Priyank, Anreddy, Nagaraju, Zhang, Yun-Kai, Wang, Yi-Jun, Chen, Yanglu, Talele, Tanaji T., Gupta, Kanav, Trombetta, Louis D., Chen, Zhe-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706835/
https://ncbi.nlm.nih.gov/pubmed/29212189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21078
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