PD173074, a selective FGFR inhibitor, reverses MRP7 (ABCC10)-mediated MDR

Multidrug resistance protein 7 (MRP7, ABCC10) is a recently identified member of the ATP-binding cassette (ABC) transporter family, which adequately confers resistance to a diverse group of antineoplastic agents, including taxanes, vinca alkaloids and nucleoside analogs among others. Clinical studie...

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Bibliographic Details
Published in:Acta Pharm Sin B
Main Authors: Anreddy, Nagaraju, Patel, Atish, Sodani, Kamlesh, Kathawala, Rishil J., Chen, Eugenie P., Wurpel, John N.D., Chen, Zhe-Sheng
Format: Artigo
Language:Inglês
Published: Elsevier 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629066/
https://ncbi.nlm.nih.gov/pubmed/26579384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2014.02.003
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