Cargando...

Large-scale purification of functional human P-glycoprotein (ABCB1)

Human P-glycoprotein (P-gp) is an ATP-binding cassette transporter that has been implicated in altering the pharmacokinetics of anticancer drugs in normal tissues and development of multidrug resistance in tumor cells via drug efflux. There is still no definitive explanation of the mechanism by whic...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Protein Expr Purif
Main Authors: Nandigama, Krishnamachary, Lusvarghi, Sabrina, Shukla, Suneet, Ambudkar, Suresh V.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600825/
https://ncbi.nlm.nih.gov/pubmed/30851394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2019.03.002
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!