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Large-scale purification of functional human P-glycoprotein (ABCB1)

Human P-glycoprotein (P-gp) is an ATP-binding cassette transporter that has been implicated in altering the pharmacokinetics of anticancer drugs in normal tissues and development of multidrug resistance in tumor cells via drug efflux. There is still no definitive explanation of the mechanism by whic...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Protein Expr Purif
Prif Awduron: Nandigama, Krishnamachary, Lusvarghi, Sabrina, Shukla, Suneet, Ambudkar, Suresh V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600825/
https://ncbi.nlm.nih.gov/pubmed/30851394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2019.03.002
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