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Large-scale purification of functional human P-glycoprotein (ABCB1)
Human P-glycoprotein (P-gp) is an ATP-binding cassette transporter that has been implicated in altering the pharmacokinetics of anticancer drugs in normal tissues and development of multidrug resistance in tumor cells via drug efflux. There is still no definitive explanation of the mechanism by whic...
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| Publicado no: | Protein Expr Purif |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6600825/ https://ncbi.nlm.nih.gov/pubmed/30851394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2019.03.002 |
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