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Effects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions
P-glycoprotein (P-gp) is a multidrug transporter that uses energy from ATP hydrolysis to export many structurally dissimilar hydrophobic and amphipathic compounds, including anticancer drugs from cells. Several structural studies on purified P-gp have been reported, but only limited and sometimes co...
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| Yayımlandı: | J Biol Chem |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5409473/ https://ncbi.nlm.nih.gov/pubmed/28283574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.771634 |
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