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Effects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions

P-glycoprotein (P-gp) is a multidrug transporter that uses energy from ATP hydrolysis to export many structurally dissimilar hydrophobic and amphipathic compounds, including anticancer drugs from cells. Several structural studies on purified P-gp have been reported, but only limited and sometimes co...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Shukla, Suneet, Abel, Biebele, Chufan, Eduardo E., Ambudkar, Suresh V.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409473/
https://ncbi.nlm.nih.gov/pubmed/28283574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.771634
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