Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum

Por Marino, Silvia, Vooijs, Marc, van der Gulden, Hanneke, Jonkers, Jos, Berns, Anton
Publicado em 2000

Frat is dispensable for canonical Wnt signaling in mammals

Por van Amerongen, Renée, Nawijn, Martijn, Franca-Koh, Jonathan, Zevenhoven, John, van der Gulden, Hanneke, Jonkers, Jos, Berns, Anton
Publicado em 2005

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer

Por Liu, Xiaoling, Holstege, Henne, van der Gulden, Hanneke, Treur-Mulder, Marcelle, Zevenhoven, John, Velds, Arno, Kerkhoven, Ron M., van Vliet, Martin H., Wessels, Lodewyk F. A., Peterse, Johannes L., Berns, Anton, Jonkers, Jos
Publicado em 2007

Somatic structural rearrangements in genetically engineered mouse mammary tumors

Por Varela, Ignacio, Klijn, Christiaan, Stephens, Phillip J, Mudie, Laura J, Stebbings, Lucy, Galappaththige, Danushka, van der Gulden, Hanneke, Schut, Eva, Klarenbeek, Sjoerd, Campbell, Peter J, Wessels, Lodewyk FA, Stratton, Michael R, Jonkers, Jos, Futreal, P Andrew, Adams, David J
Publicado em 2010

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

Por Bouwman, Peter, Aly, Amal, Escandell, Jose M., Pieterse, Mark, Bartkova, Jirina, van der Gulden, Hanneke, Hiddingh, Sanne, Thanasoula, Maria, Kulkarni, Atul, Yang, Qifeng, Haffty, Bruce G., Tommiska, Johanna, Blomqvist, Carl, Drapkin, Ronny, Adams, David J., Nevanlinna, Heli, Bartek, Jiri, Tarsounas, Madalena, Ganesan, Shridar, Jonkers, Jos
Publicado em 2010

BRCA1(185delAG) tumors may acquire therapy resistance through expression of RING-less BRCA1

Por Drost, Rinske, Dhillon, Kiranjit K., van der Gulden, Hanneke, van der Heijden, Ingrid, Brandsma, Inger, Cruz, Cristina, Chondronasiou, Dafni, Castroviejo-Bermejo, Marta, Boon, Ute, Schut, Eva, van der Burg, Eline, Wientjens, Ellen, Pieterse, Mark, Klijn, Christiaan, Klarenbeek, Sjoerd, Loayza-Puch, Fabricio, Elkon, Ran, van Deemter, Liesbeth, Rottenberg, Sven, van de Ven, Marieke, Dekkers, Dick H.W., Demmers, Jeroen A.A., van Gent, Dik C., Agami, Reuven, Balmaña, Judith, Serra, Violeta, Taniguchi, Toshiyasu, Bouwman, Peter, Jonkers, Jos
Publicado no J Clin Invest (2016)

The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin

Por Wang, Yifan, Bernhardy, Andrea J., Cruz, Cristina, Krais, John J., Nacson, Joseph, Nicolas, Emmanuelle, Peri, Suraj, van der Gulden, Hanneke, van der Heijden, Ingrid, O'Brien, Shane W., Zhang, Yong, Harrell, Maribel I., Johnson, Shawn F., Candido Dos Reis, Francisco J., Pharoah, Paul D. P., Karlan, Beth, Gourley, Charlie, Lambrechts, Diether, Chenevix-Trench, Georgia, Olsson, Håkan, Benitez, Javier J., Greene, Mark H., Gore, Martin, Nussbaum, Robert, Sadetzki, Siegal, Gayther, Simon A., Kjaer, Susanne K., D'Andrea, Alan D., Shapiro, Geoffrey I., Wiest, David L., Connolly, Denise C., Daly, Mary B., Swisher, Elizabeth M., Bouwman, Peter, Jonkers, Jos, Balmaña, Judith, Serra, Violeta, Johnson, Neil
Publicado no Cancer Res (2016)