Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy

In recent years, platinum (Pt) drugs have been found to be especially efficient to treat patients with cancers that lack a proper DNA damage response, for example, due to dysfunctional BRCA1. Despite this knowledge, we are still missing helpful markers to predict Pt response in the clinic. We have p...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer Res Commun
Main Authors: Widmer, Carmen A., Klebic, Ismar, Domanitskaya, Natalya, Decollogny, Morgane, Howald, Denise, Siffert, Myriam, Essers, Paul, Nowicka, Zuzanna, Stokar-Regenscheit, Nadine, van de Ven, Marieke, de Korte-Grimmerink, Renske, Galván, José A., Pritchard, Colin E.J., Huijbers, Ivo J., Fendler, Wojciech, Vens, Conchita, Rottenberg, Sven
פורמט: Artigo
שפה:Inglês
יצא לאור: American Association for Cancer Research 2022
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613873/
https://ncbi.nlm.nih.gov/pubmed/36467895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2767-9764.CRC-22-0208
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