Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy

In recent years, platinum (Pt) drugs have been found to be especially efficient to treat patients with cancers that lack a proper DNA damage response, for example, due to dysfunctional BRCA1. Despite this knowledge, we are still missing helpful markers to predict Pt response in the clinic. We have p...

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Detalhes bibliográficos
Publicado no:Cancer Res Commun
Main Authors: Widmer, Carmen A., Klebic, Ismar, Domanitskaya, Natalya, Decollogny, Morgane, Howald, Denise, Siffert, Myriam, Essers, Paul, Nowicka, Zuzanna, Stokar-Regenscheit, Nadine, van de Ven, Marieke, de Korte-Grimmerink, Renske, Galván, José A., Pritchard, Colin E.J., Huijbers, Ivo J., Fendler, Wojciech, Vens, Conchita, Rottenberg, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Cancer Research 2022
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613873/
https://ncbi.nlm.nih.gov/pubmed/36467895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2767-9764.CRC-22-0208
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