Pharmacodynamic Biomarker Development for PI3K Pathway Therapeutics

le Josephs, Debra H., Sarker, Debashis
Foilsithe in Transl Oncogenomics (2016)

IgE immunotherapy: A novel concept with promise for the treatment of cancer

le Josephs, Debra H, Spicer, James F, Karagiannis, Panagiotis, Gould, Hannah J, Karagiannis, Sophia N
Foilsithe 2014

Therapeutic targets and new directions for antibodies developed for ovarian cancer

le Bax, Heather J., Josephs, Debra H., Pellizzari, Giulia, Spicer, James F., Montes, Ana, Karagiannis, Sophia N.
Foilsithe in MAbs (2016)

Comparative reactivity of human IgE to cynomolgus monkey and human effector cells and effects on IgE effector cell potency

le Saul, Louise, Saul, Louise, Josephs, Debra H, Josephs, Debra H, Cutler, Keith, Cutler, Keith, Bradwell, Andrew, Bradwell, Andrew, Karagiannis, Panagiotis, Karagiannis, Panagiotis, Selkirk, Chris, Selkirk, Chris, Gould, Hannah J, Gould, Hannah J, Jones, Paul, Jones, Paul, Spicer, James F, Spicer, James F, Karagiannis, Sophia N, Karagiannis, Sophia N
Foilsithe 2014

Beta-glucan contamination of pharmaceutical products: How much should we accept?

le Barton, Claire, Vigor, Kim, Scott, Robert, Jones, Paul, Lentfer, Heike, Bax, Heather J., Josephs, Debra H., Karagiannis, Sophia N., Spicer, James F.
Foilsithe in Cancer Immunol Immunother (2016)

Chronic inflammation markers are associated with risk of pancreatic cancer in the Swedish AMORIS cohort study

le Sollie, Sam, Michaud, Dominique S., Sarker, Debashis, Karagiannis, Sophia N., Josephs, Debra H., Hammar, Niklas, Santaolalla, Aida, Walldius, Goran, Garmo, Hans, Holmberg, Lars, Jungner, Ingmar, Van Hemelrijck, Mieke
Foilsithe in BMC Cancer (2019)

Serum Immunoglobulin G Is Associated With Decreased Risk of Pancreatic Cancer in the Swedish AMORIS Study

le Sollie, Sam, Santaolalla, Aida, Michaud, Dominique S., Sarker, Debashis, Karagiannis, Sophia N., Josephs, Debra H., Hammar, Niklas, Walldius, Goran, Garmo, Hans, Holmberg, Lars, Jungner, Ingmar, Van Hemelrijck, Mieke
Foilsithe in Front Oncol (2020)

Impact of age on the toxicity of immune checkpoint inhibition

le Samani, Amit, Zhang, Shuai, Spiers, Laura, Suwaidan, Ali Abdulnabi, Merrick, Sophie, Tippu, Zayd, Payne, Miranda, Faust, Guy, Papa, Sophie, Fields, Paul, Van Hemelrijck, Mieke, Josephs, Debra H
Foilsithe in J Immunother Cancer (2020)

Effects of BRAF mutations and BRAF inhibition on immune responses to melanoma

le Ilieva, Kristina M., Correa, Isabel, Josephs, Debra H., Karagiannis, Panagiotis, Egbuniwe, Isioma U., Cafferkey, Michiala J., Spicer, James F., Harries, Mark, Nestle, Frank O., Lacy, Katie E., Karagiannis, Sophia N.
Foilsithe in Mol Cancer Ther (2014)

Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs)

le Hoffmann, Ricarda M., Coumbe, Ben G. T., Josephs, Debra H., Mele, Silvia, Ilieva, Kristina M., Cheung, Anthony, Tutt, Andrew N., Spicer, James F., Thurston, David E., Crescioli, Silvia, Karagiannis, Sophia N.
Foilsithe in Oncoimmunology (2017)

IgE Antibodies against Cancer: Efficacy and Safety

le Chauhan, Jitesh, McCraw, Alex J., Nakamura, Mano, Osborn, Gabriel, Sow, Heng Sheng, Cox, Vivienne F., Stavraka, Chara, Josephs, Debra H., Spicer, James F., Karagiannis, Sophia N., Bax, Heather J.
Foilsithe in Antibodies (Basel) (2020)

A tool kit for rapid cloning and expression of recombinant antibodies

le Dodev, Tihomir S., Karagiannis, Panagiotis, Gilbert, Amy E., Josephs, Debra H., Bowen, Holly, James, Louisa K., Bax, Heather J., Beavil, Rebecca, Pang, Marie O., Gould, Hannah J., Karagiannis, Sophia N., Beavil, Andrew J.
Foilsithe 2014

In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model

le Williams, Iwan P., Crescioli, Silvia, Sow, Heng Sheng, Bax, Heather J., Hobbs, Carl, Ilieva, Kristina M., French, Elise, Pellizzari, Giulia, Cox, Vivienne, Josephs, Debra H., Spicer, James F., Karagiannis, Sophia N., Mele, Silvia
Foilsithe in MAbs (2019)

Targeting folate receptor alpha for cancer treatment

le Cheung, Anthony, Bax, Heather J., Josephs, Debra H., Ilieva, Kristina M., Pellizzari, Giulia, Opzoomer, James, Bloomfield, Jacinta, Fittall, Matthew, Grigoriadis, Anita, Figini, Mariangela, Canevari, Silvana, Spicer, James F., Tutt, Andrew N., Karagiannis, Sophia N.
Foilsithe in Oncotarget (2016)

IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states

le Pellizzari, Giulia, Hoskin, Coran, Crescioli, Silvia, Mele, Silvia, Gotovina, Jelena, Chiaruttini, Giulia, Bianchini, Rodolfo, Ilieva, Kristina, Bax, Heather J., Papa, Sophie, Lacy, Katie E., Jensen-Jarolim, Erika, Tsoka, Sophia, Josephs, Debra H., Spicer, James F., Karagiannis, Sophia N.
Foilsithe in EBioMedicine (2019)

AllergoOncology: Expression platform development and functional profiling of an anti‐HER2 IgE antibody

le Ilieva, Kristina M., Fazekas‐Singer, Judit, Bax, Heather J., Crescioli, Silvia, Montero‐Morales, Laura, Mele, Silvia, Sow, Heng Sheng, Stavraka, Chara, Josephs, Debra H., Spicer, James F., Steinkellner, Herta, Jensen‐Jarolim, Erika, Tutt, Andrew N. J., Karagiannis, Sophia N.
Foilsithe in Allergy (2019)

BRAF inhibitors: resistance and the promise of combination treatments for melanoma

le Griffin, Merope, Scotto, Daniele, Josephs, Debra H., Mele, Silvia, Crescioli, Silvia, Bax, Heather J., Pellizzari, Giulia, Wynne, Matthew D., Nakamura, Mano, Hoffmann, Ricarda M., Ilieva, Kristina M., Cheung, Anthony, Spicer, James F., Papa, Sophie, Lacy, Katie E., Karagiannis, Sophia N.
Foilsithe in Oncotarget (2017)

Immune mediator expression signatures are associated with improved outcome in ovarian carcinoma

le Nakamura, Mano, Bax, Heather J., Scotto, Daniele, Souri, Elmira Amiri, Sollie, Sam, Harris, Robert J., Hammar, Niklas, Walldius, Goran, Winship, Anna, Ghosh, Sharmistha, Montes, Ana, Spicer, James F., Van Hemelrijck, Mieke, Josephs, Debra H., Lacy, Katie E., Tsoka, Sophia, Karagiannis, Sophia N.
Foilsithe in Oncoimmunology (2019)

AllergoOncology: Microbiota in allergy and cancer—A European Academy for Allergy and Clinical Immunology position paper

le Untersmayr, Eva, Bax, Heather J., Bergmann, Christoph, Bianchini, Rodolfo, Cozen, Wendy, Gould, Hannah J., Hartmann, Karin, Josephs, Debra H., Levi‐Schaffer, Francesca, Penichet, Manuel L., O'Mahony, Liam, Poli, Aurelie, Redegeld, Frank A., Roth‐Walter, Franziska, Turner, Michelle C., Vangelista, Luca, Karagiannis, Sophia N., Jensen‐Jarolim, Erika
Foilsithe in Allergy (2019)

IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

le Nakamura, Mano, Souri, Elmira Amiri, Osborn, Gabriel, Laddach, Roman, Chauhan, Jitesh, Stavraka, Chara, Lombardi, Sara, Black, Anna, Khiabany, Atousa, Khair, Duaa O., Figini, Mariangela, Winship, Anna, Ghosh, Sharmistha, Montes, Ana, Spicer, James F., Bax, Heather J., Josephs, Debra H., Lacy, Katie E., Tsoka, Sophia, Karagiannis, Sophia N.
Foilsithe in Cancers (Basel) (2020)