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Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs)
Antibody-drug conjugates (ADCs) are emerging as effective tools in cancer therapy, combining the antibody's exquisite specificity for the target antigen-expressing cancer cell together with the cytotoxic potency of the payload. Much success stems from the rational design of “toxic warheads”, ch...
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Publicado no: | Oncoimmunology |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5769674/ https://ncbi.nlm.nih.gov/pubmed/29375935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1395127 |
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