Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs)

Antibody-drug conjugates (ADCs) are emerging as effective tools in cancer therapy, combining the antibody's exquisite specificity for the target antigen-expressing cancer cell together with the cytotoxic potency of the payload. Much success stems from the rational design of “toxic warheads”, ch...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Oncoimmunology
मुख्य लेखकों: Hoffmann, Ricarda M., Coumbe, Ben G. T., Josephs, Debra H., Mele, Silvia, Ilieva, Kristina M., Cheung, Anthony, Tutt, Andrew N., Spicer, James F., Thurston, David E., Crescioli, Silvia, Karagiannis, Sophia N.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis 2017
विषय:
Review
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769674/
https://ncbi.nlm.nih.gov/pubmed/29375935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1395127
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