In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model

IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and represent a key challenge f...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:MAbs
Päätekijät: Williams, Iwan P., Crescioli, Silvia, Sow, Heng Sheng, Bax, Heather J., Hobbs, Carl, Ilieva, Kristina M., French, Elise, Pellizzari, Giulia, Cox, Vivienne, Josephs, Debra H., Spicer, James F., Karagiannis, Sophia N., Mele, Silvia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2019
Aiheet:
Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927758/
https://ncbi.nlm.nih.gov/pubmed/31769737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1685349
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