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In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model
IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and represent a key challenge f...
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| 出版年: | MAbs |
|---|---|
| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6927758/ https://ncbi.nlm.nih.gov/pubmed/31769737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1685349 |
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