In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model

IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and represent a key challenge f...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:MAbs
Egile Nagusiak: Williams, Iwan P., Crescioli, Silvia, Sow, Heng Sheng, Bax, Heather J., Hobbs, Carl, Ilieva, Kristina M., French, Elise, Pellizzari, Giulia, Cox, Vivienne, Josephs, Debra H., Spicer, James F., Karagiannis, Sophia N., Mele, Silvia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2019
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927758/
https://ncbi.nlm.nih.gov/pubmed/31769737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1685349
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