Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields

Monoclonal antibodies find broad application as therapy for various types of cancer by employing multiple mechanisms of action against tumors. Manipulating the Fc-mediated functions of antibodies that engage immune effector cells, such as NK cells, represents a strategy to influence effector cell ac...

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Wydane w:Front Immunol
Główni autorzy: Ilieva, Kristina M., Fazekas-Singer, Judit, Achkova, Daniela Y., Dodev, Tihomir S., Mele, Silvia, Crescioli, Silvia, Bax, Heather J., Cheung, Anthony, Karagiannis, Panagiotis, Correa, Isabel, Figini, Mariangela, Marlow, Rebecca, Josephs, Debra H., Beavil, Andrew J., Maher, John, Spicer, James F., Jensen-Jarolim, Erika, Tutt, Andrew N., Karagiannis, Sophia N.
Format: Artigo
Język:Inglês
Wydane: Frontiers Media S.A. 2017
Hasła przedmiotowe:
Immunology
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604060/
https://ncbi.nlm.nih.gov/pubmed/28959256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01112
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