Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields

Monoclonal antibodies find broad application as therapy for various types of cancer by employing multiple mechanisms of action against tumors. Manipulating the Fc-mediated functions of antibodies that engage immune effector cells, such as NK cells, represents a strategy to influence effector cell ac...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Immunol
Päätekijät: Ilieva, Kristina M., Fazekas-Singer, Judit, Achkova, Daniela Y., Dodev, Tihomir S., Mele, Silvia, Crescioli, Silvia, Bax, Heather J., Cheung, Anthony, Karagiannis, Panagiotis, Correa, Isabel, Figini, Mariangela, Marlow, Rebecca, Josephs, Debra H., Beavil, Andrew J., Maher, John, Spicer, James F., Jensen-Jarolim, Erika, Tutt, Andrew N., Karagiannis, Sophia N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2017
Aiheet:
Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604060/
https://ncbi.nlm.nih.gov/pubmed/28959256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01112
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