Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase

por Rajendra, Eeson, Venkitaraman, Ashok R.
Publicado em 2010

The UPS: a promising target for breast cancer treatment

por Sato, Ko, Rajendra, Eeson, Ohta, Tomohiko
Publicado em 2008

Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPases

por Rajendra, Eeson, Garaycoechea, Juan I., Patel, Ketan J., Passmore, Lori A.
Publicado no Nucleic Acids Res (2014)

Sampling the conformational space of the catalytic subunit of human γ-secretase

por Bai, Xiao-chen, Rajendra, Eeson, Yang, Guanghui, Shi, Yigong, Scheres, Sjors HW
Publicado no eLife (2015)

The Carboxyl Terminus of Brca2 Links the Disassembly of Rad51 Complexes to Mitotic Entry

por Ayoub, Nabieh, Rajendra, Eeson, Su, Xinyi, Jeyasekharan, Anand D., Mahen, Robert, Venkitaraman, Ashok R.
Publicado em 2009

An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells

por Hochegger, Helfrid, Dejsuphong, Donniphat, Sonoda, Eiichiro, Saberi, Alihossein, Rajendra, Eeson, Kirk, Jane, Hunt, Tim, Takeda, Shunichi
Publicado em 2007

The Genetic and Biochemical Basis of FANCD2 Monoubiquitination

por Rajendra, Eeson, Oestergaard, Vibe H., Langevin, Frédéric, Wang, Meng, Dornan, Gillian L., Patel, Ketan J., Passmore, Lori A.
Publicado em 2014

The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange

por Shivji, Mahmud K. K., Mukund, Shreyas R., Rajendra, Eeson, Chen, Shaoxia, Short, Judith M., Savill, Jane, Klenerman, David, Venkitaraman, Ashok R.
Publicado em 2009

DNA damage regulates the mobility of Brca2 within the nucleoplasm of living cells

por Jeyasekharan, Anand D., Ayoub, Nabieh, Mahen, Robert, Ries, Jonas, Esposito, Alessandro, Rajendra, Eeson, Hattori, Hiroyoshi, Kulkarni, Rajan P., Venkitaraman, Ashok R.
Publicado em 2010

Interrogation of the Protein-Protein Interactions between Human BRCA2 BRC Repeats and RAD51 Reveals Atomistic Determinants of Affinity

por Cole, Daniel J., Rajendra, Eeson, Roberts-Thomson, Meredith, Hardwick, Bryn, McKenzie, Grahame J., Payne, Mike C., Venkitaraman, Ashok R., Skylaris, Chris-Kriton
Publicado em 2011

Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage

por Gibbs-Seymour, Ian, Oka, Yasuyoshi, Rajendra, Eeson, Weinert, Brian T., Passmore, Lori A., Patel, Ketan J., Olsen, Jesper V., Choudhary, Chunaram, Bekker-Jensen, Simon, Mailand, Niels
Publicado no Mol Cell (2015)

Scc2 Is a Potent Activator of Cohesin’s ATPase that Promotes Loading by Binding Scc1 without Pds5

por Petela, Naomi J., Gligoris, Thomas G., Metson, Jean, Lee, Byung-Gil, Voulgaris, Menelaos, Hu, Bin, Kikuchi, Sotaro, Chapard, Christophe, Chen, Wentao, Rajendra, Eeson, Srinivisan, Madhusudhan, Yu, Hongtao, Löwe, Jan, Nasmyth, Kim A.
Publicado no Mol Cell (2018)

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization

por Jeyasekharan, Anand D, Liu, Yang, Hattori, Hiroyoshi, Pisupati, Venkat, Jonsdottir, Asta Bjork, Rajendra, Eeson, Lee, Miyoung, Sundaramoorthy, Elayanambi, Schlachter, Simon, Kaminski, Clemens, Ofir-Rosenfeld, Yaara, Sato, Ko, Savill, Jane, Ayoub, Nabieh, Venkitaraman, Ashok R
Publicado em 2013

Structure of the Fanconi anemia monoubiquitin ligase complex

por Shakeel, Shabih, Rajendra, Eeson, Alcón, Pablo, O’Reilly, Francis, Chorev, Dror S., Maslen, Sarah, Degliesposti, Gianluca, Russo, Christopher J., He, Shaoda, Hill, Chris H., Skehel, J. Mark, Scheres, Sjors H.W., Patel, Ketan J., Rappsilber, Juri, Robinson, Carol V., Passmore, Lori A.
Publicado no Nature (2019)

Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

por Zatreanu, Diana, Robinson, Helen M. R., Alkhatib, Omar, Boursier, Marie, Finch, Harry, Geo, Lerin, Grande, Diego, Grinkevich, Vera, Heald, Robert A., Langdon, Sophie, Majithiya, Jayesh, McWhirter, Claire, Martin, Niall M. B., Moore, Shaun, Neves, Joana, Rajendra, Eeson, Ranzani, Marco, Schaedler, Theresia, Stockley, Martin, Wiggins, Kimberley, Brough, Rachel, Sridhar, Sandhya, Gulati, Aditi, Shao, Nan, Badder, Luned M., Novo, Daniela, Knight, Eleanor G., Marlow, Rebecca, Haider, Syed, Callen, Elsa, Hewitt, Graeme, Schimmel, Joost, Prevo, Remko, Alli, Christina, Ferdinand, Amanda, Bell, Cameron, Blencowe, Peter, Bot, Chris, Calder, Mathew, Charles, Mark, Curry, Jayne, Ekwuru, Tennyson, Ewings, Katherine, Krajewski, Wojciech, MacDonald, Ellen, McCarron, Hollie, Pang, Leon, Pedder, Chris, Rigoreau, Laurent, Swarbrick, Martin, Wheatley, Ed, Willis, Simon, Wong, Ai Ching, Nussenzweig, Andre, Tijsterman, Marcel, Tutt, Andrew, Boulton, Simon J., Higgins, Geoff S., Pettitt, Stephen J., Smith, Graeme C. M., Lord, Christopher J.
Publicado no Nat Commun (2021)