Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage

We show that central components of the Fanconi anemia (FA) DNA repair pathway, the tumor suppressor proteins FANCI and FANCD2 (the ID complex), are SUMOylated in response to replication fork stalling. The ID complex is SUMOylated in a manner that depends on the ATR kinase, the FA ubiquitin ligase co...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Gibbs-Seymour, Ian, Oka, Yasuyoshi, Rajendra, Eeson, Weinert, Brian T., Passmore, Lori A., Patel, Ketan J., Olsen, Jesper V., Choudhary, Chunaram, Bekker-Jensen, Simon, Mailand, Niels
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2015
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416315/
https://ncbi.nlm.nih.gov/pubmed/25557546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.12.001
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