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Structure of the Fanconi anemia monoubiquitin ligase complex
The Fanconi Anemia (FA) pathway repairs DNA damage caused by endogenous and chemotherapy-induced DNA crosslinks, and responds to replication stress(1,2). Genetic inactivation of this pathway impairs development, prevents blood production and promotes cancer(1,3). The key molecular step in the FA pat...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858856/ https://ncbi.nlm.nih.gov/pubmed/31666700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1703-4 |
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