Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns

由 Mateo, Lidia, Duran-Frigola, Miquel, Gris-Oliver, Albert, Palafox, Marta, Scaltriti, Maurizio, Razavi, Pedram, Chandarlapaty, Sarat, Arribas, Joaquin, Bellet, Meritxell, Serra, Violeta, Aloy, Patrick
發表在 Genome Med (2020)

MEK plus PI3K/mTORC1/2 therapeutic efficacy is impacted by TP53 mutation in preclinical models of colorectal cancer

由 García-García, Celina, Rivas, Martín A., Ibrahim, Yasir H., Calvo, María Teresa, Gris-Oliver, Albert, Rodríguez, Olga, Grueso, Judit, Antón, Pilar, Guzmán, Marta, Aura, Claudia, Nuciforo, Paolo, Jessen, Katti, Argilés, Guillem, Dienstmann, Rodrigo, Bertotti, Andrea, Trusolino, Livio, Matito, Judit, Vivancos, Ana, Chicote, Irene, Palmer, Héctor G., Tabernero, Josep, Scaltriti, Maurizio, Baselga, José, Serra, Violeta
發表在 Clin Cancer Res (2015)

PI3K activation promotes resistance to eribulin in HER2-negative breast cancer

由 Gris-Oliver, Albert, Ibrahim, Yasir H., Rivas, Martín A., García-García, Celina, Sánchez-Guixé, Mònica, Ruiz-Pace, Fiorella, Viaplana, Cristina, Pérez-García, José M., Llombart-Cussac, Antonio, Grueso, Judit, Parés, Mireia, Guzmán, Marta, Rodríguez, Olga, Anton, Pilar, Cozar, Patricia, Calvo, Maria Teresa, Bruna, Alejandra, Arribas, Joaquín, Caldas, Carlos, Dienstmann, Rodrigo, Nuciforo, Paolo, Oliveira, Mafalda, Cortés, Javier, Serra, Violeta
發表在 Br J Cancer (2021)

PIM1 kinase regulates cell death, tumor growth and chemotherapy response revealing a novel target in triple-negative breast cancer

由 Brasó-Maristany, Fara, Filosto, Simone, Catchpole, Steven, Marlow, Rebecca, Quist, Jelmar, Francesch-Domenech, Erika, Plumb, Darren A., Zakka, Leila, Gazinska, Patrycja, Liccardi, Gianmaria, Meier, Pascal, Gris-Oliver, Albert, Cheang, Maggie Chon U, Perdrix-Rosell, Anna, Shafat, Manar, Noël, Elodie, Patel, Nirmesh, McEachern, Kristen, Scaltriti, Maurizio, Castel, Pau, Noor, Farzana, Buus, Richard, Mathew, Sumi, Watkins, Johnathan, Serra, Violeta, Marra, Pierfrancesco, Grigoriadis, Anita, Tutt, Andrew N.
發表在 Nat Med (2016)

In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer

由 Zagorac, Ivana, Fernandez-Gaitero, Sara, Penning, Renske, Post, Harm, Bueno, Maria J., Mouron, Silvana, Manso, Luis, Morente, Manuel M., Alonso, Soledad, Serra, Violeta, Muñoz, Javier, Gómez-López, Gonzalo, Lopez-Acosta, Jose Francisco, Jimenez-Renard, Veronica, Gris-Oliver, Albert, Al-Shahrour, Fatima, Piñeiro-Yañez, Elena, Montoya-Suarez, Jose Luis, Apala, Juan V., Moreno-Torres, Amalia, Colomer, Ramon, Dopazo, Ana, Heck, Albert J. R., Altelaar, Maarten, Quintela-Fandino, Miguel
發表在 Nat Commun (2018)

Genetic alterations in the PI3K/AKT pathway and baseline AKT activity define AKT inhibitor sensitivity in breast cancer patient-derived xenografts

由 Gris-Oliver, Albert, Palafox, Marta, Monserrat, Laia, Brasó-Maristany, Fara, Òdena, Andreu, Sánchez-Guixé, Mònica, Ibrahim, Yasir H., Villacampa, Guillermo, Grueso, Judit, Parés, Mireia, Guzmán, Marta, Rodríguez, Olga, Bruna, Alejandra, Hirst, Caroline S., Barnicle, Alan, de Bruin, Elza, Reddy, Avinash, Schiavon, Gaia, Arribas, Joaquín, Mills, Gordon B., Caldas, Carlos, Dienstmann, Rodrigo, Prat, Aleix, Nuciforo, Paolo, Razavi, Pedram, Scaltriti, Maurizio, Turner, Nicholas C., Saura, Cristina, Davies, Barry R., Oliveira, Mafalda, Serra, Violeta
發表在 Clin Cancer Res (2020)

A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation

由 Castroviejo‐Bermejo, Marta, Cruz, Cristina, Llop‐Guevara, Alba, Gutiérrez‐Enríquez, Sara, Ducy, Mandy, Ibrahim, Yasir Hussein, Gris‐Oliver, Albert, Pellegrino, Benedetta, Bruna, Alejandra, Guzmán, Marta, Rodríguez, Olga, Grueso, Judit, Bonache, Sandra, Moles‐Fernández, Alejandro, Villacampa, Guillermo, Viaplana, Cristina, Gómez, Patricia, Vidal, Marc, Peg, Vicente, Serres‐Créixams, Xavier, Dellaire, Graham, Simard, Jacques, Nuciforo, Paolo, Rubio, Isabel T, Dientsmann, Rodrigo, Barrett, J Carl, Caldas, Carlos, Baselga, José, Saura, Cristina, Cortés, Javier, Déas, Olivier, Jonkers, Jos, Masson, Jean‐Yves, Cairo, Stefano, Judde, Jean‐Gabriel, O'Connor, Mark J, Díez, Orland, Balmaña, Judith, Serra, Violeta
發表在 EMBO Mol Med (2018)