Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence

le Morancho, Beatriz, Martínez-Barriocanal, Águeda, Villanueva, Josep, Arribas, Joaquín
Foilsithe in Breast Cancer Res (2015)

TACE is required for the activation of the EGFR by TGF-α in tumors

le Borrell-Pagès, Maria, Rojo, Federico, Albanell, Joan, Baselga, Josep, Arribas, Joaquín
Foilsithe 2003

N-terminal cleavage of proTGFα occurs at the cell surface by a TACE-independent activity

le Juanes, Pedro P., Ferreira, Laura, Montero, Juan Carlos, Arribas, Joaquín, Pandiella, Atanasio
Foilsithe 2005

The Carboxy-terminal Cysteine of the Tetraspanin L6 Antigen Is Required for Its Interaction with SITAC, a Novel PDZ Protein

le Borrell-Pagès, Maria, Fernández-Larrea, Juan, Borroto, Aldo, Rojo, Federico, Baselga, José, Arribas, Joaquín
Foilsithe 2000

The Cleavage of Semaphorin 3C Induced by ADAMTS1 Promotes Cell Migration

le Esselens, Cary, Malapeira, Jordi, Colomé, Núria, Casal, Carmen, Rodríguez-Manzaneque, Juan Carlos, Canals, Francesc, Arribas, Joaquín
Foilsithe 2010

Proteomic Identification of Desmoglein 2 and Activated Leukocyte Cell Adhesion Molecule as Substrates of ADAM17 and ADAM10 by Difference Gel Electrophoresis

le Bech-Serra, Joan J., Santiago-Josefat, Belén, Esselens, Cary, Saftig, Paul, Baselga, José, Arribas, Joaquín, Canals, Francesc
Foilsithe 2006

Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation

le Anido, Judit, Scaltriti, Maurizio, Bech Serra, Joan Josep, Josefat, Belén Santiago, Rojo Todo, Federico, Baselga, José, Arribas, Joaquín
Foilsithe 2006

Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis

le Martín-Pérez, Rosa, Yerbes, Rosario, Mora-Molina, Rocío, Cano-González, Ana, Arribas, Joaquín, Mazzone, Massimiliano, López-Rivas, Abelardo, Palacios, Carmen
Foilsithe in Oncotarget (2017)

Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts

le Morancho, Beatriz, Zacarías-Fluck, Mariano, Esgueva, Antonio, Bernadó-Morales, Cristina, Cosimo, Serena Di, Prat, Aleix, Cortés, Javier, Arribas, Joaquín, Rubio, Isabel T.
Foilsithe in Oncotarget (2016)

HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503

le Gorbatenko, Andrej, Søkilde, Rolf, Sorensen, Ester E., Newie, Inga, Persson, Helena, Morancho, Beatriz, Arribas, Joaquin, Litman, Thomas, Rovira, Carlos, Pedersen, Stine Falsig
Foilsithe in Sci Rep (2019)

Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growth

le Chandarlapaty, Sarat, Scaltriti, Maurizio, Angelini, Pierdavide, Ye, Qing, Guzman, Marta, Hudis, Clifford A., Norton, Larry, Solit, David B., Arribas, Joaquin, Baselga, Jose, Rosen, Neal
Foilsithe 2009

Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns

le Mateo, Lidia, Duran-Frigola, Miquel, Gris-Oliver, Albert, Palafox, Marta, Scaltriti, Maurizio, Razavi, Pedram, Chandarlapaty, Sarat, Arribas, Joaquin, Bellet, Meritxell, Serra, Violeta, Aloy, Patrick
Foilsithe in Genome Med (2020)

Acquired cancer cell resistance to T cell bispecific antibodies and CAR T targeting HER2 through JAK2 down-modulation

le Arenas, Enrique J., Martínez-Sabadell, Alex, Rius Ruiz, Irene, Román Alonso, Macarena, Escorihuela, Marta, Luque, Antonio, Fajardo, Carlos Alberto, Gros, Alena, Klein, Christian, Arribas, Joaquín
Foilsithe in Nat Commun (2021)

HER2 Carboxyl-terminal Fragments Regulate Cell Migration and Cortactin Phosphorylation

le García-Castillo, Jesús, Pedersen, Kim, Angelini, Pier-Davide, Bech-Serra, Joan Josep, Colomé, Núria, Cunningham, Matthew Paul, Parra-Palau, Josep Lluis, Canals, Francesc, Baselga, José, Arribas, Joaquín
Foilsithe 2009

Silencing of adaptor protein SH3BP2 reduces KIT/PDGFRA receptors expression and impairs gastrointestinal stromal tumors growth

le Serrano‐Candelas, Eva, Ainsua‐Enrich, Erola, Navinés‐Ferrer, Arnau, Rodrigues, Paulo, García‐Valverde, Alfonso, Bazzocco, Sarah, Macaya, Irati, Arribas, Joaquín, Serrano, César, Sayós, Joan, Arango, Diego, Martin, Margarita
Foilsithe in Mol Oncol (2018)

Ibrutinib Exerts Potent Antifibrotic and Antitumor Activities in Mouse Models of Pancreatic Adenocarcinoma

le Massó-Vallés, Daniel, Jauset, Toni, Serrano, Erika, Sodir, Nicole M., Pedersen, Kim, Affara, Nesrine I., Whitfield, Jonathan R., Beaulieu, Marie-Eve, Evan, Gerard I., Elias, Laurence, Arribas, Joaquín, Soucek, Laura
Foilsithe in Cancer Res (2015)

The Second Generation Antibody-Drug Conjugate SYD985 Overcomes Resistances to T-DM1

le Nadal-Serrano, Mercedes, Morancho, Beatriz, Escrivá-de-Romaní, Santiago, Bernadó Morales, Cristina, Luque, Antonio, Escorihuela, Marta, Espinosa Bravo, Martín, Peg, Vicente, Dijcks, Fred A., Dokter, Wim H.A., Cortés, Javier, Saura, Cristina, Arribas, Joaquín
Foilsithe in Cancers (Basel) (2020)

A Naturally Occurring HER2 Carboxy-Terminal Fragment Promotes Mammary Tumor Growth and Metastasis

le Pedersen, Kim, Angelini, Pier-Davide, Laos, Sirle, Bach-Faig, Alba, Cunningham, Matthew P., Ferrer-Ramón, Cristina, Luque-García, Antonio, García-Castillo, Jesús, Parra-Palau, Josep Lluis, Scaltriti, Maurizio, y Cajal, Santiago Ramón, Baselga, José, Arribas, Joaquín
Foilsithe 2009

High HER2 protein levels correlate with increased survival in breast cancer patients treated with anti‐HER2 therapy

le Nuciforo, Paolo, Thyparambil, Sheeno, Aura, Claudia, Garrido-Castro, Ana, Vilaro, Marta, Peg, Vicente, Jimenez, José, Vicario, Rocio, Cecchi, Fabiola, Hoos, William, Burrows, Jon, Hembrough, Todd, Ferreres, Juan Carles, Perez-Garcia, José, Arribas, Joaquin, Cortes, Javier, Scaltriti, Maurizio
Foilsithe in Mol Oncol (2015)

Clinical benefit of lapatinib-based therapy in patients with HER2-positive breast tumors co-expressing the truncated p95HER2 receptor

le Scaltriti, Maurizio, Chandarlapaty, Sarat, Prudkin, Ludmila, Aura, Claudia, Jimenez, José, Angelini, Pier Davide, Sánchez, Gertrudis, Guzman, Marta, Parra, Josep Lluis, Ellis, Catherine, Gagnon, Robert, Koehler, Maria, Gomez, Henry, Geyer, Charles, Cameron, David, Arribas, Joaquin, Rosen, Neal, Baselga, José
Foilsithe 2010