Adenovirus i-Leader Truncation Bioselected Against Cancer-associated Fibroblasts to Overcome Tumor Stromal Barriers

Por Puig-Saus, Cristina, Gros, Alena, Alemany, Ramon, Cascalló, Manel
Publicado em 2012

Urokinase-Type Plasminogen Activator Receptor Transcriptionally Controlled Adenoviruses Eradicate Pancreatic Tumors and Liver Metastasis in Mouse Models

Por Huch, Meritxell, Gros, Alena, José, Anabel, González, Juan Ramon, Alemany, Ramon, Fillat, Cristina
Publicado em 2009

Verapamil Enhances the Antitumoral Efficacy of Oncolytic Adenoviruses

Por Gros, Alena, Puig, Cristina, Guedan, Sonia, Rojas, Juan José, Alemany, Ramon, Cascallo, Manel
Publicado em 2010

Hyaluronidase Expression by an Oncolytic Adenovirus Enhances Its Intratumoral Spread and Suppresses Tumor Growth

Por Guedan, Sonia, Rojas, Juan José, Gros, Alena, Mercade, Elena, Cascallo, Manel, Alemany, Ramon
Publicado em 2010

Use of CD137 up-regulation to identify T cell receptors specifically reactive with mutated tumor associated antigens from tumor infiltrating lymphocytes

Por Parkhurst, Maria, Gros, Alena, Anna, Pasetto, Tran, Eric, Crystal, Jessica S, Prickett, Todd, Robbins, Paul, Rosenberg, Steven A
Publicado no J Immunother Cancer (2015)

Phenotype and Function of T Cells Infiltrating Visceral Metastases from Gastrointestinal Cancers and Melanoma: Implications for Adoptive Cell Transfer Therapy

Por Turcotte, Simon, Gros, Alena, Hogan, Katherine, Tran, Eric, Hinrichs, Christian S., Wunderlich, John R., Dudley, Mark E., Rosenberg, Steven A.
Publicado em 2013

Targeting of HPV-16+ epithelial cancer cells by TCR gene engineered T cells directed against E6

Por Draper, Lindsey M., Kwong, Mei Li, Gros, Alena, Stevanović, Sanja, Tran, Eric, Kerkar, Sid, Raffeld, Mark, Rosenberg, Steven A., Hinrichs, Christian S.
Publicado no Clin Cancer Res (2015)

Toward cell transfer immunotherapy against patient-specific mutations in gastrointestinal cancers

Por Tran, Eric, Ahmadzadeh, Mojgan, Gros, Alena, Turcotte, Simon, Robbins, Paul F, Lu, Yong Chen, Li, Yong, Wunderlich, John, Gartner, Jared, Hogan, Katherine, Yang, James, Rosenberg, Steven
Publicado no J Immunother Cancer (2014)

High frequency CD8+PD-1+ TCR clonotypes isolated from fresh melanomas display anti-tumor activity

Por Anna, Pasetto, Gros, Alena, Robbins, Paul F, Prickett, Todd D, Deniger, Drew C, Matus-Nicodemus, Rodrigo, Parkhurst, Maria R, Crystal, Jessica S, Trebska-Mcgowan, Kasia, Rosenberg, Steven A
Publicado no J Immunother Cancer (2015)

Durable complete response in a patient with metastatic melanoma following adoptive transfer of autologous T cells recognizing 10 mutated tumor antigens

Por Prickett, Todd D, Crystal, Jessica S, Gartner, Jared J, Xin, Yao, Anna, Pasetto, Gros, Alena, Lu, Yong-Chen, Li, Yong, El-Gamil, Mona, Rosenberg, Steven A, Robbins, Paul
Publicado no J Immunother Cancer (2015)

Diversity of mutated antigen recognition by tumor infiltrating lymphocytes from patients with metastatic melanoma

Por Crystal, Jessica S, Prickett, Todd D, Gartner, Jared J, Parkhurst, Maria R, Lu, Yong-Chen, Gros, Alena, Li, Yong, Trebska-Mcgowan, Kasia, El-Gamil, Mona, Rosenberg, Steven A, Robbins, Paul F
Publicado no J Immunother Cancer (2015)

Selection of circulating PD-1+ lymphocytes from cancer patients enriches for tumor-reactive and mutation-specific lymphocytes

Por Gros, Alena, Tran, Eric, Parkhurst, Maria R, Anna, Pasetto, Ilyas, Sadia, Prickett, Todd D, Gartner, Jared J, Robbins, Paul F, Crystal, Jessica S, Trebska-Mcgowan, Kasia, Wudnerlich, John R, Yang, James C, Rosenberg, Steven A
Publicado no J Immunother Cancer (2015)

Tumor- and neoantigen-reactive T-cell receptors can be identified based on their frequency in fresh tumor

Por Pasetto, Anna, Gros, Alena, Robbins, Paul F, Deniger, Drew C, Prickett, Todd D, Matus-Nicodemos, Rodrigo, Douek, Daniel C, Howie, Bryan, Robins, Harlan, Parkhurst, Maria R, Gartner, Jared, Trebska-McGowan, Katarzyna, Crystal, Jessica S, Rosenberg, Steven A
Publicado no Cancer Immunol Res (2016)

Durable Complete Response from Metastatic Melanoma after Transfer of Autologous T Cells Recognizing 10 Mutated Tumor Antigens

Por Prickett, Todd D., Crystal, Jessica S., Cohen, Cyrille J., Pasetto, Anna, Parkhurst, Maria R., Gartner, Jared J., Yao, Xin, Wang, Rong, Gros, Alena, Li, Yong F., El-Gamil, Mona, Trebska-McGowan, Kasia, Rosenberg, Steven A., Robbins, Paul F.
Publicado no Cancer Immunol Res (2016)

PD-1 identifies the patient-specific CD8(+) tumor-reactive repertoire infiltrating human tumors

Por Gros, Alena, Robbins, Paul F., Yao, Xin, Li, Yong F., Turcotte, Simon, Tran, Eric, Wunderlich, John R., Mixon, Arnold, Farid, Shawn, Dudley, Mark E., Hanada, Ken-ichi, Almeida, Jorge R., Darko, Sam, Douek, Daniel C., Yang, James C., Rosenberg, Steven A.
Publicado em 2014

Ionic immune suppression within the tumour microenvironment limits T cell effector function

Por Eil, Robert, Vodnala, Suman K, Clever, David, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Pan, Jenny H, Palmer, Douglas C, Gros, Alena, Yamamoto, Tori N, Patel, Shashank J, Guittard, Geoffrey C, Yu, Zhiya, Carbonaro, Valentina, Okkenhaug, Klaus, Schrump, David S, Linehan, W Marston, Roychoudhuri, Rahul, Restifo, Nicholas P
Publicado no Nature (2016)

Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics

Por Crompton, Joseph G., Sukumar, Madhusudhanan, Roychoudhuri, Rahul, Clever, David, Gros, Alena, Eil, Robert, Tran, Eric, Hanada, Ken-ichi, Yu, Zhiya, Palmer, Douglas C., Kerkar, Sid P., Michalek, Ryan D., Upham, Trevor, Leonardi, Anthony, Aquavella, Nicholas, Wang, Ena, Marincola, Francesco M., Gattinoni, Luca, Muranski, Pawel, Sundrud, Mark S., Klebanoff, Christopher A., Rosenberg, Steven A., Fearon, Douglas T., Restifo, Nicholas P.
Publicado no Cancer Res (2014)

Type-1-cytokines synergize with oncogene inhibition to induce tumor growth arrest

Por Acquavella, Nicolas, Clever, David, Yu, Zhiya, Roelke-Parker, Melody, Palmer, Douglas C., Xi, Liqiang, Pflicke, Holger, Ji, Yun, Gros, Alena, Hanada, Ken-ichi, Goldlust, Ian S., Mehta, Gautam U., Klebanoff, Christopher A., Crompton, Joseph G., Sukumar, Madhusudhanan, Morrow, James J., Franco, Zulmarie, Gattinoni, Luca, Liu, Hui, Wang, Ena, Marincola, Francesco, Stroncek, David F., Lee, Chyi-Chia R., Raffeld, Mark, Bosenberg, Marcus W., Roychoudhuri, Rahul, Restifo, Nicholas P.
Publicado no Cancer Immunol Res (2014)

Memory T cell–driven differentiation of naive cells impairs adoptive immunotherapy

Por Klebanoff, Christopher A., Scott, Christopher D., Leonardi, Anthony J., Yamamoto, Tori N., Cruz, Anthony C., Ouyang, Claudia, Ramaswamy, Madhu, Roychoudhuri, Rahul, Ji, Yun, Eil, Robert L., Sukumar, Madhusudhanan, Crompton, Joseph G., Palmer, Douglas C., Borman, Zachary A., Clever, David, Thomas, Stacy K., Patel, Shashankkumar, Yu, Zhiya, Muranski, Pawel, Liu, Hui, Wang, Ena, Marincola, Francesco M., Gros, Alena, Gattinoni, Luca, Rosenberg, Steven A., Siegel, Richard M., Restifo, Nicholas P.
Publicado no J Clin Invest (2015)

Cancer regression and neurologic toxicity following anti-MAGE-A3 TCR gene therapy

Por Morgan, Richard A., Chinnasamy, Nachimuthu, Abate-Daga, Daniel D, Gros, Alena, Robbins, Paul F., Zheng, Zhili, Feldman, Steven A., Yang, James C., Sherry, Richard M., Phan, Giao Q., Hughes, Marybeth S., Kammula, Udai S., Miller, Akemi D., Hessman, Crystal J., Stewart, Ashley A., Restifo, Nicholas P., Quezado, Martha M., Alimchandani, Meghna, Rosenberg, Avi Z., Nath, Avindra, Wang, Tongguang, Bielekova, Bibiana, Wuest, Simone C., Nirmala, Akula, McMahon, Francis J., Wilde, Susanne, Mosetter, Barbara, Schendel, Dolores J., Laurencot, Carolyn M., Rosenberg, Steven A
Publicado em 2013