Double or nothing on cancer immunotherapy

Por Hanada, Ken-ichi, Restifo, Nicholas P
Publicado no Nat Biotechnol (2013)

Characterization of a Novel Non-classical T-cell Clone with Broad Reactivity against Human Renal Cell Carcinomas (RCCs)

Por Wang, Qiong J., Hanada, Ken-ichi, Yang, James C.
Publicado em 2008

Molecular identification of an MHC-independent ligand recognized by a human α/β T-cell receptor

Por Hanada, Ken-ichi, Wang, Qiong J., Inozume, Takashi, Yang, James C.
Publicado em 2011

Augmenting adoptive T cell therapy through universal chimeric costimulators

Por Hanada, Ken-ichi, Bagadia, Prachi, Wang, Qiong, Griffith, Kayla, Yang, James
Publicado em 2013

IL-17 Secreted by Tumor Reactive T Cells Induces IL-8 Release by Human Renal Cancer Cells

Por Inozume, Takashi, Hanada, Ken-ichi, Wang, Qiong J., Yang, James C.
Publicado no J Immunother (2009)

Multiple Protein-Protein Interactions by RNA Polymerase I-Associated Factor PAF49 and Role of PAF49 in rRNA Transcription

Por Yamamoto, Kazuo, Yamamoto, Mika, Hanada, Ken-ichi, Nogi, Yasuhisa, Matsuyama, Toshifumi, Muramatsu, Masami
Publicado em 2004

An effective mouse model for adoptive cancer immunotherapy targeting neoantigens

Por Hanada, Ken-ichi, Yu, Zhiya, Chappell, Gabrielle R., Park, Adam S., Restifo, Nicholas P.
Publicado no JCI Insight (2019)

Distinctive Features of the Differentiated Phenotype and Infiltration of Tumor-reactive Lymphocytes in Clear Cell Renal Cell Carcinoma

Por Wang, Qiong J., Hanada, Ken-ichi, Robbins, Paul F., Li, Yong F., Yang, James C.
Publicado em 2012

Development of a Genetically-Modified Novel T-Cell Receptor for Adoptive Cell Transfer against Renal Cell carcinoma

Por Wang, Qiong J., Hanada, Ken-ichi, Feldman, Steven A., Zhao, Yangbing, Inozume, Takashi, Yang, James C.
Publicado em 2011

Identification of T-cell Receptors Targeting KRAS-mutated Human Tumors

Por Wang, Qiong J., Yu, Zhiya, Griffith, Kayla, Hanada, Ken-ichi, Restifo, Nicholas P., Yang, James C.
Publicado no Cancer Immunol Res (2015)

Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytes

Por Abate-Daga, Daniel, Hanada, Ken-ichi, Davis, Jeremy L., Yang, James C., Rosenberg, Steven A., Morgan, Richard A.
Publicado em 2013

Pre-clinical Evaluation of Chimeric Antigen Receptors Targeting CD70-Expressing Cancers

Por Wang, Qiong J., Yu, Zhiya, Hanada, Ken-ichi, Patel, Krishna, Kleiner, David, Restifo, Nicholas P., Yang, James C.
Publicado no Clin Cancer Res (2016)

Selection of CD8(+)PD-1(+) lymphocytes in fresh human melanomas enriches for tumor-reactive T-cells

Por Inozume, Takashi, Hanada, Ken-ichi, Wang, Qiong J., Ahmadzadeh, Mojgan, Wunderlich, John R., Rosenberg, Steven A., Yang, James C.
Publicado em 2010

Tetramer based approach for efficient identification and isolation of neo-antigen specific CD8 T cells from peripheral blood (PBL) of patients with metastatic cancers

Por Bharathan, Mini, Trebska-McGowan, Katarina, Anna, Pasetto, Deniger, Drew C, Hanada, Ken-ichi, Gartner, Jared J, Yang, James C, Rosenberg, Steven A, Robbins, Paul F
Publicado no J Immunother Cancer (2015)

Personalized immunotherapy for non-small cell lung cancer through identification of tumor-specific mutations by next generation sequencing and adoptive transfer of tumor infiltrati...

Por Hanada, Ken-ichi, Chow, Christopher, Hoyos, Raul Gil, Gartner, Jared J, Prickett, Todd D, Somerville, Robert, Hogan, Katherine, Robbins, Paul F, Rosenberg, Steven A, Yang, James C
Publicado no J Immunother Cancer (2015)

An antigenic peptide produced by reverse splicing and double asparagine deamidation

Por Dalet, Alexandre, Robbins, Paul F., Stroobant, Vincent, Vigneron, Nathalie, Li, Yong F., El-Gamil, Mona, Hanada, Ken-ichi, Yang, James C., Rosenberg, Steven A., Van den Eynde, Benoît J.
Publicado em 2011

Vaccine-Stimulated, Adoptively Transferred CD8(+) T Cells Traffic Indiscriminately and Ubiquitously while Mediating Specific Tumor Destruction

Por Palmer, Douglas C., Balasubramaniam, Sanjeeve, Hanada, Ken-ichi, Wrzesinski, Claudia, Yu, Zhiya, Farid, Shahram, Theoret, Marc R., Hwang, Leroy N., Klebanoff, Christopher A., Gattinoni, Luca, Goldstein, Allan L., Yang, James C., Restifo, Nicholas P.
Publicado em 2004

Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus

Por Van Laethem, François, Saba, Ingrid, Lu, Jinghua, Bhattacharya, Abhisek, Tai, Xuguang, Guinter, Terry I., Engelhardt, Britta, Alag, Amala, Rojano, Mirelle, Ashe, Jennifer M., Hanada, Ken-ichi, Yang, James C., Sun, Peter D., Singer, Alfred
Publicado no Front Immunol (2020)

αβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificities

Por Tikhonova, Anastasia N., Van Laethem, François, Hanada, Ken-ichi, Lu, Jinghua, Pobezinsky, Leonid A., Hong, Changwan, Guinter, Terry I., Jeurling, Susanna K., Bernhardt, Günter, Park, Jung-Hyun, Yang, James C., Sun, Peter D., Singer, Alfred
Publicado em 2011

Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells

Por Takahashi, Yoshiyuki, Harashima, Nanae, Kajigaya, Sachiko, Yokoyama, Hisayuki, Cherkasova, Elena, McCoy, J. Philip, Hanada, Ken-ichi, Mena, Othon, Kurlander, Roger, Abdul, Tawab, Srinivasan, Ramaprasad, Lundqvist, Andreas, Malinzak, Elizabeth, Geller, Nancy, Lerman, Michael I., Childs, Richard W.
Publicado em 2008