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Molecular identification of an MHC-independent ligand recognized by a human α/β T-cell receptor
During an analysis of T-cell responses against human renal cell carcinoma (RCC), we identified a CD4(+) T-cell line that showed TCR-mediated recognition and lysis of nearly all RCC lines regardless of MHC type. We have now elucidated the nature of the ligand for this α/β TCR, and it contains no MHC-...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100692/ https://ncbi.nlm.nih.gov/pubmed/21300979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-317743 |
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