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Development of a Genetically-Modified Novel T-Cell Receptor for Adoptive Cell Transfer against Renal Cell carcinoma

A novel α/β T-cell clone with broad reactivity against human clear cell renal cell carcinomas (RCC) was generated from a patient with renal cancer. The T-cell receptor (TCR) from this clone recognizes soluble TNF-related apoptosis inducing ligand bound to death receptor 4, a complex found on the sur...

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Bibliografiske detaljer
Main Authors: Wang, Qiong J., Hanada, Ken-ichi, Feldman, Steven A., Zhao, Yangbing, Inozume, Takashi, Yang, James C.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061346/
https://ncbi.nlm.nih.gov/pubmed/21255579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.01.002
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