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Development of a Genetically-Modified Novel T-Cell Receptor for Adoptive Cell Transfer against Renal Cell carcinoma
A novel α/β T-cell clone with broad reactivity against human clear cell renal cell carcinomas (RCC) was generated from a patient with renal cancer. The T-cell receptor (TCR) from this clone recognizes soluble TNF-related apoptosis inducing ligand bound to death receptor 4, a complex found on the sur...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061346/ https://ncbi.nlm.nih.gov/pubmed/21255579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.01.002 |
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