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Coevolution of T-cell receptors with MHC and non-MHC ligands
The structure and amino acid diversity of the T-cell receptor (TCR), similar in nature to that of Fab portions of antibodies, would suggest these proteins have a nearly infinite capacity to recognize antigen. Yet all currently defined native T cells expressing an α and β chain in their TCR can only...
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| Published in: | Immunol Rev |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4544829/ https://ncbi.nlm.nih.gov/pubmed/26284470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12327 |
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