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Coevolution of T-cell receptors with MHC and non-MHC ligands

The structure and amino acid diversity of the T-cell receptor (TCR), similar in nature to that of Fab portions of antibodies, would suggest these proteins have a nearly infinite capacity to recognize antigen. Yet all currently defined native T cells expressing an α and β chain in their TCR can only...

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Foilsithe in:Immunol Rev
Main Authors: Castro, Caitlin C., Luoma, Adrienne M., Adams, Erin J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544829/
https://ncbi.nlm.nih.gov/pubmed/26284470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12327
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