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Molecular identification of an MHC-independent ligand recognized by a human α/β T-cell receptor

During an analysis of T-cell responses against human renal cell carcinoma (RCC), we identified a CD4(+) T-cell line that showed TCR-mediated recognition and lysis of nearly all RCC lines regardless of MHC type. We have now elucidated the nature of the ligand for this α/β TCR, and it contains no MHC-...

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書誌詳細
主要な著者: Hanada, Ken-ichi, Wang, Qiong J., Inozume, Takashi, Yang, James C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100692/
https://ncbi.nlm.nih.gov/pubmed/21300979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-317743
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