Identification of lineage-specifying cytokines that signal all CD8-cytotoxic lineage fate decisions in the thymus

av Etzensperger, Ruth, Kadakia, Tejas, Tai, Xuguang, Alag, Amala, Guinter, Terry I., Egawa, Takeshi, Erman, Batu, Singer, Alfred
I publikationen Nat Immunol (2017)

Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus

av McCaughtry, Tom M., Etzensperger, Ruth, Alag, Amala, Tai, Xuguang, Kurtulus, Sema, Park, Jung-Hyun, Grinberg, Alex, Love, Paul, Feigenbaum, Lionel, Erman, Batu, Singer, Alfred
Publicerad 2012

Foxp3 transcription factor is pro-apoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals

av Tai, Xuguang, Erman, Batu, Alag, Amala, Mu, Jie, Kimura, Motoko, Katz, Gil, Guinter, Terry, McCaughtry, Tom, Etzensperger, Ruth, Feigenbaum, Lionel, Singer, Dinah S., Singer, Alfred
Publicerad 2013

E-protein–regulated expression of CXCR4 adheres preselection thymocytes to the thymic cortex

av Kadakia, Tejas, Tai, Xuguang, Kruhlak, Michael, Wisniewski, Jan, Hwang, Il-Young, Roy, Sumedha, Guinter, Terry I., Alag, Amala, Kehrl, John H., Zhuang, Yuan, Singer, Alfred
I publikationen J Exp Med (2019)

Let-7 miRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function

av Pobezinsky, Leonid A., Etzensperger, Ruth, Jeurling, Susanna, Alag, Amala, Kadakia, Tejas, McCaughtry, Tom M., Kimura, Motoko Y., Sharrow, Susan O., Guinter, Terry I., Feigenbaum, Lionel, Singer, Alfred
I publikationen Nat Immunol (2015)

Coreceptor gene imprinting governs thymocyte lineage fate

av Adoro, Stanley, McCaughtry, Thomas, Erman, Batu, Alag, Amala, Van Laethem, François, Park, Jung-Hyun, Tai, Xuguang, Kimura, Motoko, Wang, Lie, Grinberg, Alex, Kubo, Masato, Bosselut, Remy, Love, Paul, Singer, Alfred
Publicerad 2012

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

av Park, Jung-Hyun, Adoro, Stanley, Guinter, Terry, Erman, Batu, Alag, Amala S, Catalfamo, Marta, Kimura, Motoko Y, Cui, Yongzhi, Lucas, Philip J, Gress, Ronald E, Kubo, Masato, Hennighausen, Lothar, Feigenbaum, Lionel, Singer, Alfred
Publicerad 2010

Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus

av Van Laethem, François, Saba, Ingrid, Lu, Jinghua, Bhattacharya, Abhisek, Tai, Xuguang, Guinter, Terry I., Engelhardt, Britta, Alag, Amala, Rojano, Mirelle, Ashe, Jennifer M., Hanada, Ken-ichi, Yang, James C., Sun, Peter D., Singer, Alfred
I publikationen Front Immunol (2020)