E-protein–regulated expression of CXCR4 adheres preselection thymocytes to the thymic cortex

Preselection thymocytes are normally retained in the thymic cortex, but the mechanisms responsible remain incompletely understood. We now report that deletion of genes encoding the E-protein transcription factors E2A and HEB disorders chemokine receptor expression on developing thymocytes to allow e...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Kadakia, Tejas, Tai, Xuguang, Kruhlak, Michael, Wisniewski, Jan, Hwang, Il-Young, Roy, Sumedha, Guinter, Terry I., Alag, Amala, Kehrl, John H., Zhuang, Yuan, Singer, Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683992/
https://ncbi.nlm.nih.gov/pubmed/31201207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182285
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