E-protein–regulated expression of CXCR4 adheres preselection thymocytes to the thymic cortex

Preselection thymocytes are normally retained in the thymic cortex, but the mechanisms responsible remain incompletely understood. We now report that deletion of genes encoding the E-protein transcription factors E2A and HEB disorders chemokine receptor expression on developing thymocytes to allow e...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Kadakia, Tejas, Tai, Xuguang, Kruhlak, Michael, Wisniewski, Jan, Hwang, Il-Young, Roy, Sumedha, Guinter, Terry I., Alag, Amala, Kehrl, John H., Zhuang, Yuan, Singer, Alfred
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683992/
https://ncbi.nlm.nih.gov/pubmed/31201207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182285
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