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CD8 Coreceptor Extinction in Signaled CD4(+)CD8(+) Thymocytes: Coordinate Roles for Both Transcriptional and Posttranscriptional Regulatory Mechanisms in Developing Thymocytes
T-cell development in the thymus is characterized by changing expression patterns of CD4 and CD8 coreceptor molecules and by changes in CD4 and CD8 gene transcription. In response to T-cell receptor (TCR) signals, thymocytes progress through developmental transitions, such as conversion of CD4(+)CD8...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC85715/ https://ncbi.nlm.nih.gov/pubmed/10805728 |
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