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CD8 Coreceptor Extinction in Signaled CD4(+)CD8(+) Thymocytes: Coordinate Roles for Both Transcriptional and Posttranscriptional Regulatory Mechanisms in Developing Thymocytes

T-cell development in the thymus is characterized by changing expression patterns of CD4 and CD8 coreceptor molecules and by changes in CD4 and CD8 gene transcription. In response to T-cell receptor (TCR) signals, thymocytes progress through developmental transitions, such as conversion of CD4(+)CD8...

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Bibliografiske detaljer
Main Authors: Cibotti, Ricardo, Bhandoola, Avinash, Guinter, Terry I., Sharrow, Susan O., Singer, Alfred
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85715/
https://ncbi.nlm.nih.gov/pubmed/10805728
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